Actively Recruiting

Phase 3
Age: 45Years - 65Years
All Genders
NCT05576818

Effect of Synbiotic as an Adjuvant Therapy in the Treatment of Parkinson's Disease

Led by Tanta University · Updated on 2025-04-10

66

Participants Needed

1

Research Sites

152 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to investigate the possible efficacy and safety of synbiotic preparation of Lactobacillus acidophilus probiotic with prebiotic fibers as an adjuvant therapy in the treatment of Parkinson's disease

CONDITIONS

Official Title

Effect of Synbiotic as an Adjuvant Therapy in the Treatment of Parkinson's Disease

Who Can Participate

Age: 45Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 45 and 65 years old
  • Both sexes
  • Patients with Parkinson's disease on dopamine replacement therapy
  • Modified Hoehn and Yahr stage, MHY 1-4
Not Eligible

You will not qualify if you...

  • Use of antibiotics therapy in the preceding month
  • Use of other probiotic products in the preceding two weeks
  • Scheduled for or history of gastrointestinal tract surgery
  • Known allergy to probiotics
  • Receiving artificial enteral or intravenous nutrition
  • Presence of depression and/or psychosis
  • Taking antioxidant and/or anti-inflammatory medications
  • Having hyperthyroidism
  • Having inflammatory conditions and/or conditions involving oxidative stress
  • Smokers
  • Modified Hoehn and Yahr stage MHY 5

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tanta University

Tanta, El Gharbia, Egypt

Actively Recruiting

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Research Team

M

Mohamed E Ramadan

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Effect of Synbiotic as an Adjuvant Therapy in the Treatment of Parkinson's Disease | DecenTrialz