Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06855758

Effect of Terlipressin for Intraoperative Blood Pressure Management in Kidney Transplantation

Led by Beijing Friendship Hospital · Updated on 2025-03-20

150

Participants Needed

1

Research Sites

116 weeks

Total Duration

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AI-Summary

What this Trial Is About

Prospective double blind randomized controlled trial. By randomizing patients undergoing kidney transplantation into a conventional catecholamine drug (dobutamine) blood pressure maintenance group and a terlipressin-complexed dobutamine group, the investigators compared the effect of intraoperative blood pressure maintenance and the dosage of the vasoactive drug, postoperative graft function, delayed graft function, and other related complications between the two groups, in order to demonstrate whether the use of terlipressin for blood pressure regulation during kidney transplantation is superior to the existing treatments.

CONDITIONS

Official Title

Effect of Terlipressin for Intraoperative Blood Pressure Management in Kidney Transplantation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with end-stage renal disease aged 18 years or above
Not Eligible

You will not qualify if you...

  • Simultaneous multiple organ transplantation
  • Known allergy to study medication
  • Known pregnancy status
  • Cancellation of surgery due to grafts or personal reasons
  • Persistent severe preoperative hypertension that may not require intraoperative vasoactive medication
  • Any other reason deemed unsuitable by the supervising physician or anesthesiologist on duty

AI-Screening

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Trial Site Locations

Total: 1 location

1

Beijing Friendship Hospital

Beijing, China

Actively Recruiting

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Research Team

W

Wenhe Yang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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