Actively Recruiting

Phase 2
All Genders
NCT06981767

Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus

Led by Cairo University · Updated on 2026-03-03

42

Participants Needed

1

Research Sites

16 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Bromelain, an enzyme extract derived from pineapples, has shown promise due to its anti-inflammatory and wound-healing properties. However, its efficacy in treating oral mucosal ulcers remains unexplored. This study aims to provide clinical evidence on the efficacy of bromelain for managing OLP, potentially offering a safer and more effective treatment option.

CONDITIONS

Official Title

Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients suffering from symptomatic OLP
  • Patients free from any visible oral lesions other than OLP
  • Patients who agreed to take the supplied interventions
  • Patients who agree to participate in the study
  • Patients who accept to sign the informed consent
Not Eligible

You will not qualify if you...

  • Patients suffering from any systemic disease
  • Treatment with any systemic steroids, immunosuppressive drugs, or non-steroidal anti-inflammatory drugs within the last 8 weeks
  • Treatment with any oral topical medications within the last 4 weeks
  • Pregnant and lactating mothers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cairo University

Cairo, Cairo Governorate, Egypt

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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