Actively Recruiting
Effect of Tranexamic Acid (TXA) on Reduction of Postoperative Blood Transfusion
Led by Gregory M Georgiadis MD · Updated on 2025-08-07
200
Participants Needed
1
Research Sites
469 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Tranexamic Acid (TXA) is an antifibrolytic medication used in total hip and knee arthroplasty to reduce the need for intraoperative and postoperative blood transfusions. Limited research is available on its use in hip fracture patients. We hypothesize that the use of TXA preoperatively, perioperatively, and postoperatively will decrease blood loss and need for blood transfusion postoperatively.
CONDITIONS
Official Title
Effect of Tranexamic Acid (TXA) on Reduction of Postoperative Blood Transfusion
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Over the age of 60 years
- Hip fracture requiring surgical intervention
- Signs consent and agrees to participate
You will not qualify if you...
- Under the age of 60
- Does not sign consent or refuses participation
- Known hypersensitivity to tranexamic acid
- Multiple acute fractures
- Creatinine clearance <30
- History of seizures
- Active hormone therapy
- History of coagulation abnormality
- History of deep vein thrombosis (DVT) or pulmonary embolism (PE) within the last year or history or recurrent DVT/PE
- Myocardial infarction (MI) and/or stents within the past year
- History of intracranial hemorrhage
- Acquired defective color vision
- Patients admitted directly to nursing units or surgery without stay in the Emergency Center
- Patients who sustain fracture while hospitalized at ProMedica Toledo Hospital
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
ProMedica Toledo Hospital
Toledo, Ohio, United States, 43606
Actively Recruiting
Research Team
K
Kristin Gardner, MSN, RN
CONTACT
M
Michelle Barhite, RPh
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here