Actively Recruiting
Effect of Transcranial Alternative Current Stimulation at Alpha Frequency (α-tACS) on Stressed Healthy Subjects
Led by Hôpital le Vinatier · Updated on 2024-03-07
40
Participants Needed
1
Research Sites
209 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
stress. Notably, several studies reported that stress could alter impulsivity, source monitoring, and time perception. Several mechanisms are involved in the response to a stress factor, among them the hypothalamic-pituitary-adrenal (HPA) axis. The cortisol reactivity (it means the cortisol secretion after the exposure to a standardized stress factor) is a reliable tool to assess the function of HPA. Cortisol secretion is bidirectionally influenced by the prefrontal cortex (PFC), which is involved in the expression and regulation of stress as well. The asymmetry of the alpha band (AFα) is a well known electrophysiological parameter to assess the function of PFC. More precisely, AFα is arising a growing interest, as it is believed to be correlated with the cortisol reactivity. Modifying this asymmetry could influence the stress response. Transcranial Alternating Current Stimulation (tACS) consists in delivering a sinusoidal alternating current between two electrodes placed on the scalp at a predefined frequency. Previous studious reported that tACS, if delivered at the alpha frequency, increased the alpha band in the stimulated areas
CONDITIONS
Official Title
Effect of Transcranial Alternative Current Stimulation at Alpha Frequency (α-tACS) on Stressed Healthy Subjects
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Right-handed men and women aged between 18 and 45 years
- Women must be using hormonal contraception
- Must have given written informed consent
- Must be affiliated with a social security scheme
- Must be able to speak and read French
You will not qualify if you...
- Contraindication to transcranial alternating current stimulation (tACS)
- Current psychiatric disorder as classified in the DSM-5
- Regular use of any psychotropic drug or beta blockers
- Recent exposure to a traumatic event
- Any debilitating condition making the procedure not feasible
- Pregnancy
AI-Screening
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Trial Site Locations
Total: 1 location
1
Centre Hospitalier Le Vinatier
Bron, AURA, France, 69678 CEDEX
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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