Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
ID06548711

Effect of Transcutaneous Acupoint Electrical Stimulation on Postoperative Cough in Lung Cancer Patients Randomized, Double-Blind, Controlled Clinical Trial

Led by Kong Fanming · Updated on 2025-09-08

84

Participants Needed

1

Research Sites

8 weeks

Total Duration

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AI-Summary

What this Trial Is About

Researchers are studying the effects of Transcutaneous Acupoint Electrical Stimulation (TAES) on improving cough symptoms in patients who have undergone lung cancer surgery. This trial aims to evaluate changes in cough severity using various measures, including the Cough Symptom Score (CSS), Visual Analog Scale (VAS), and the Leicester Cough Questionnaire-Mandarin Chinese version (LCQ-MC). The study also seeks to assess patients' overall evaluation of the treatment and identify those who may benefit most from TAES as a non-drug therapy for postoperative cough. Participants are randomly assigned to one of two groups: the TEAS group receiving actual electrical stimulation at specific acupuncture points, and the sham TEAS group receiving electrode placement without active stimulation. The treatment involves applying electrode patches to cleaned skin while the patient is seated, with electrical pulses delivered at a frequency of 2 Hz in the active group. The study includes treatment and follow-up periods, with assessments conducted before treatment, at the end of treatment (week 2), and two weeks post-treatment (week 4). Throughout the study, participants complete clinical observation forms and undergo evaluations including the LCQ-MC to measure cough-related quality of life. Clinical data are collected and analyzed to report results. Patients are monitored for treatment adherence and any adverse effects. The total participation lasts for at least four weeks, covering baseline, treatment, and follow-up assessments to observe changes in cough symptoms and overall treatment impact.

CONDITIONS

Brief Title

Effect of Transcutaneous Acupoint Electrical Stimulation (TAES) on Postoperative Cough in Lung Cancer

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 80 years old
  • Surgery performed under general anesthesia for radical lung cancer resection or lung cancer resection with lymph node dissection
  • Pathological confirmation of primary lung cancer after surgery
  • Persistent dry cough lasting 2 weeks or more after lung surgery
  • Consciousness with ability to express opinions clearly and voluntary informed consent signed
Not Eligible

You will not qualify if you...

  • Acute respiratory system diseases diagnosed within 1 month
  • Pneumonia diagnosed by chest X-ray
  • History of asthma or tuberculosis
  • Uncontrolled hyperthyroidism, severe hypertension, heart disease, systemic infection, coagulation disorders, or other severe systemic diseases
  • Use of steroid drugs within past 3 months
  • Use of angiotensin-converting enzyme inhibitors within past 6 months
  • Surgical incisions, skin allergies, wounds, or infections in the treatment area
  • Inability to tolerate or withdrawal from transcutaneous acupoint electrical stimulation
  • Contraindications to electrical stimulation or implanted electrophysiological devices
  • Pregnancy or breastfeeding

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 2 weeks

Participants receive transcutaneous acupoint electrical stimulation (TAES) or sham treatment to evaluate its effect on postoperative cough in lung cancer patients.

Regular treatment sessions during the 2-week period

Follow-up

Duration - 2 weeks

Participants are monitored for changes in cough symptoms 2 weeks after the end of treatment.

1 follow-up visit

Trial Site Locations

Total: 1 location

1

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

Tianjin, Tianjin Municipality, China, 300193

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Research Team

F

Fanming Kong, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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