Impact of Tucking on Semen Quality in Adult Trans Women Compared to Those Who Do Not Tuck A Case-Control Study

What this Trial Is About

Researchers are investigating the effects of tucking and wearing tight underwear on semen quality in adult trans women before starting gender-affirming hormone therapy GAHT. This observational case-control study aims to clarify whether these practices contribute to reduced semen quality and whether this effect is reversible. The study includes 40 trans women, divided into two groups based on whether they practice tucking or not, to assess differences in semen quality and related hormonal and quality of life parameters. Participants will provide semen and blood samples after 2-7 days of abstinence for initial assessment. Those who practice tucking will then abstain from this practice for at least 73 days, after which another set of samples and assessments will be collected. Quality of life questionnaires will also be completed at both time points. Participants may choose to preserve sperm through cryopreservation before beginning GAHT. Throughout the study, semen analyses are conducted following WHO guidelines, alongside blood tests measuring hormones such as LH, FSH, estradiol, and testosterone. The study also records lifestyle and demographic data, including BMI, substance use, and medical history. Researchers will evaluate semen concentration, motility, volume, hormonal changes, and quality of life over the 3-month period to better understand the impact of tucking and tight underwear on fertility in trans women.

The Effect of Tucking on Semen Quality of Adult Trans Women