Actively Recruiting
Comparing the Effects of Two Dietary Supplements, Cynacol and Metacol, on Cholesterol Levels in Adults with Mild Hypercholesterolemia
Led by Fondazione IRCCS Policlinico San Matteo di Pavia · Updated on 2025-12-19
40
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of two dietary supplements, Cynacol and Metacol, on patients with mild hypercholesterolemia. The study aims to compare how these supplements influence LDL cholesterol LDL-C levels after 90 days of use. Secondary goals include assessing changes in total cholesterol TC, non-HDL cholesterol, apolipoprotein B apoB, triglycerides Tg, and HDL cholesterol, while monitoring for any adverse events related to the supplements. Participants will be randomized into two groups one receiving Cynacol, which contains artichoke dry extract, naringin, Silybum marianum dry extract, flaxseed oil, vitamin E, and sunflower oil the other receiving Metacol, which contains coenzyme Q10, monacolin K, and flaxseed oil. Both supplements are taken as two capsules daily after dinner for a 90-day period. Standardized diet and physical activity advice will be provided alongside supplementation. During the study, participants will have several visits including screening, baseline, and follow-ups at 45 and 90 days. At these visits, medical history, vital signs, and blood samples will be collected to measure lipid profiles and other laboratory tests. Researchers will track changes in cholesterol levels and monitor for any adverse events. The study duration for each participant is approximately 3 months, focusing on the changes in lipid levels and supplement safety.
CONDITIONS
Brief Title
Effect of Two Food Supplements on Lipid Profile in Patients With Mild Hypercholesterolemia
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