Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06588270

Effect of Virtual Reality-based Therapy on Negative Symptoms in People with Schizophrenia

Led by Hospital de la Florida Dra. Eloiza Diaz · Updated on 2024-09-19

102

Participants Needed

1

Research Sites

174 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A randomised, controlled, double-blind clinical trial will be carried out to evaluate the effectiveness of a VR assisted treatment for negative symptoms in people with schizophrenia. Patients with a standardised diagnosis of schizophrenia meeting the inclusion criteria will receive 12 weekly sessions of VR assisted therapy plus treatment as usual (TAU). A control group will be exposed to a neutral VR environment plus TAU. The hypothesis is that patients who are treated with active VR assisted therapy will have less negative symptoms as rated by the PANSS-N scale, compared to the control group. The protocol was approved by the hospital ethics committee of the Servicio de Salud Metropolitano Suroriente. Patients sign an informed consent form, from which they may withdraw at any point during the intervention.

CONDITIONS

Official Title

Effect of Virtual Reality-based Therapy on Negative Symptoms in People with Schizophrenia

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of schizophrenia confirmed by a psychiatrist using CIE-10 criteria
  • Age between 18 and 65 years old
  • Receiving outpatient care
  • Clinically stable with no psychiatric hospitalizations in the last 6 months and not currently awaiting hospitalization
  • No active substance abuse disorder except nicotine
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Previous diagnosis of learning disability according to ICD-10 or clinical history
  • Difficulties with verbal expression due to language or medical reasons
  • Deafness or blindness
  • Physical disabilities preventing use of VR devices
  • Predominant positive symptoms (PANNS-C > 0)
  • Catatonic symptoms
  • Previous diagnosis of epilepsy
  • Neurodegenerative disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital Clínico La Florida

Santiago, Santiago Metropolitan, Chile

Actively Recruiting

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Research Team

J

Javiera Libuy, MD

CONTACT

J

Jonathan Alarcón, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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