Actively Recruiting
Effect of Visual Retraining After Stroke
Led by University of Rochester · Updated on 2025-07-16
100
Participants Needed
1
Research Sites
382 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This project is intended to collect data using standard clinical tests and psychophysics to quantify the effect of visual cortical damage on the structure of the residual visual system, visual perception, spatial awareness, and brain function. The investigators will also assess the effect of intensive visual retraining on the residual visual system, processing of visual information and the use of such information in real-world situations following damage. This research is intended to improve our understanding of the consequences of permanent visual system damage in humans, of methods that can be used to reverse visual loss, and of brain mechanisms by which visual recovery is achieved.
CONDITIONS
Official Title
Effect of Visual Retraining After Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between 21 and 80 years of age
- Residents of the United States or Canada
- Unilateral stroke or stroke-like damage to the primary visual cortex or its immediate afferent white matter
- Reliable visual field defects in both eyes large enough to enclose a 5-degree diameter visual stimulus
- Able to fixate on visual targets reliably for 1000 milliseconds
- Must have a home computer (desktop or laptop) and reliable internet access
- Willing, able, and competent to provide informed consent
- Normal cognitive abilities, able to understand written and oral instructions in English
- Competent and responsible adults able to complete visual training at home independently
- Control subjects must report no history of neurological disorder and be competent and responsible as determined by the Principal Investigator
You will not qualify if you...
- Past or present eye disease interfering with visual acuity
- Best corrected visual acuity worse than 20/40 in either eye
- Damage to the dorsal Lateral Geniculate Nucleus
- Diffuse whole brain degenerative processes
- History of traumatic brain injury
- Any other brain damage that could interfere with training or outcome measures
- Documented history of drug or alcohol abuse
- Currently taking neuroactive medications that impact training
- Presence of cognitive or seizure disorders
- One-sided attentional neglect
- Subjects unable or not competent to perform the visual training exercises
- Control subjects with damage to the visual system or active nervous system disease
- Control subjects with cognitive or seizure disorders
- Control subjects with best corrected visual acuity worse than 20/40
- Control subjects with vision field loss from ocular disease or disorder
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Rochester Medical Center
Rochester, New York, United States, 14642
Actively Recruiting
Research Team
E
Evan Burr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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