Vitamin D3 Supplementation Effects on Brain Waves in Male Parkinsons Disease Patients with Low Vitamin D Levels

What this Trial Is About

Researchers are studying whether vitamin D3 supplements can affect brain waves in male patients with Parkinsons disease who have low vitamin D levels. This experimental self-controlled trial focuses on men aged 51 to 70 with Parkinsons disease up to stage 3 and confirmed vitamin D deficiency. The goal is to see if taking vitamin D3 changes brain electrical activity as measured by quantitative electroencephalogram QEEG. Participants will take a vitamin D3 capsule orally at a dose of 50,000 IU once a week for 8 weeks. Before starting the supplementation, their vitamin D levels and brain activity will be measured, and these assessments will be repeated after the 8-week treatment period. Brain waves will be recorded using a specialized EEG device analyzing various frequency bands including alpha, beta, theta, and delta. During the study, participants will visit the medical university for evaluations including blood tests for vitamin D levels and EEG recordings both before and after the supplementation period. Researchers will analyze changes in brain wave power and frequency using statistical methods. Participants are asked to bring back empty vitamin D capsule strips for adherence monitoring. The study is designed to last just over eight weeks from the start of treatment to final evaluation.

Effect of Vitamin D3 on Brain Waves in Male Parkinson's Patients With Low Vitamin D: A qEEG Study