Actively Recruiting
Effect of Vitamin D3 Supplementation on Brain Waves in Male Epileptic Patients With Hypovitaminosis D
Led by Bangladesh Medical University · Updated on 2025-07-31
15
Participants Needed
1
Research Sites
10 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is an experimental study (interventional self-controlled trial, pretest-post test design). The goal of this clinical trial is to evaluate the effect of vitamin D3 supplementation on quantitative EEG in male epileptic patients with hypovitaminosis D. . The main question it aims to answer is: Vitamin D3 supplementation has effect on brain waves in male epileptic patients with hypovitaminosis D. Researcher will compare the effect of Vitamin D3 supplementation on brain waves in male epileptic patients with hypovitaminosis D with their pre-intervention (baseline) condition on brain waves to assess whether there will be any improvement of brain electrical activity by quantitative electroencephalogram (QEEG). Participants will: Take Vitamin D3 orally for 8 weeks (50,000IU/week) Visit the medical university after 8 weeks for evaluation of serum 25 (OH) D level and quantitative electroencephalogram (QEEG) Must bring the empty strips of Vitamin D supplement with them during their visit
CONDITIONS
Official Title
Effect of Vitamin D3 Supplementation on Brain Waves in Male Epileptic Patients With Hypovitaminosis D
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed male patients with epilepsy by a neurologist with at least two unprovoked (or reflex) seizures occurring more than 24 hours apart
- Hypovitaminosis D (serum vitamin D less than 30 ng/ml)
- Body mass index between 20 and 24 kg/m8
- Taking enzyme-inducing antiepileptic drugs (such as Carbamazepine, Phenytoin, Phenobarbital) for 6 months to 2 years
- Not taking medications affecting the central nervous system other than antiepileptic drugs
- Apparently normal physical health
You will not qualify if you...
- Patients with absence seizures
- Taking certain antiepileptic drugs (Sodium valproate, Ethosuximide, Oxcarbazepine, Topiramate, Lamotrigine, Levetiracetam)
- Smokers
- Alcohol consumers
- Known allergy to vitamin D3
- Patients with hypertension
- Patients with thyroid disorders
- Patients with diabetes mellitus
- Patients with kidney disease
- Patients with liver disease
- Patients with high blood calcium levels (hypercalcemia)
AI-Screening
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Trial Site Locations
Total: 1 location
1
Bangladesh Medical University
Dhaka, Shahbag, Dhaka, Bangladesh, 1000
Actively Recruiting
Research Team
R
Registrar, BMU
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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