Actively Recruiting

Phase Not Applicable
Age: 51Years - 70Years
MALE
NCT07084597

Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male Parkinson's Disease Patients With Hypovitaminosis D

Led by Bangladesh Medical University · Updated on 2025-07-29

15

Participants Needed

1

Research Sites

13 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to see the effect of vitamin D3 supplementation on cardiac autonomic nerve function in male Parkinson's disease patients with hypovitaminosis D Main questions it aims to answer are: 1. Does vitamin D improves heart rate variability(HRV) in male Parkinson's disease patients ? 2. Does vitamin D improves cardiac autonomic nerve function in male Parkinson's disease patients ? It is a self control trial. Vitamin D3 deficient Parkinson's disease participants will a. undergo through baseline HRV test b. Then they will take vitamin D3 capsule 50000 IU once in a week for 8 consecutive weeks c. Then after intervention with vitamin D supplementation post interventional HRV will be done. Researcher will compare pre intervention(pre test) and post intervention(post test) value of HRV

CONDITIONS

Official Title

Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male Parkinson's Disease Patients With Hypovitaminosis D

Who Can Participate

Age: 51Years - 70Years
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Male patients with Parkinson's disease diagnosed by neurologist with unilateral or bilateral involvement and mild to moderate disability according to Hoehn and Yahr scale (I-III)
  • Age between 51 and 70 years
  • Body Mass Index (BMI) between 18.5 and 24.9 kg/m2
  • Vitamin D3 deficient or insufficient
  • Currently on Levodopa medication
Not Eligible

You will not qualify if you...

  • History of drug abuse including alcoholism
  • Use of antioxidant vitamin supplements
  • Use of lipid lowering medications
  • Use of antihypertensive drugs
  • Use of anti-arrhythmic drugs
  • Use of sedative medications
  • Severe cardiovascular disorders
  • Severe neurological disorders
  • Severe respiratory disorders
  • Severe renal insufficiency (serum creatinine > 1.5 mg/dl, acute or chronic kidney disease)
  • Severe endocrine disease
  • Severe arthritis
  • Severe liver diseases
  • Severe neoplastic disease
  • Severe psychiatric disorder
  • Current use of iron, zinc, calcium, magnesium, or multivitamin supplements
  • Currently performing yoga or breathing exercises
  • Hypercalcemia

AI-Screening

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Trial Site Locations

Total: 1 location

1

Bangladesh Medical University

Dhaka, Shahbag, Bangladesh, 1000

Actively Recruiting

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Research Team

R

Registrar BMU

CONTACT

J

Jobayda Jobayda, MBBS,MD resident,Phase B

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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