Actively Recruiting
A Study to See If Taking Zolpidem Improves Recovery After Lumbar Spine Fusion Surgery for Degenerative Lumbar Disease
Led by University of Southern California · Updated on 2026-05-01
140
Participants Needed
1
Research Sites
99 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying patients with degenerative lumbar disease who are undergoing one- to three-level spinal fusion surgery to see if taking zolpidem around the time of surgery improves patient-reported outcomes. This randomized controlled trial compares zolpidem to a placebo to evaluate its effects following lumbar spine fusion. Participants will be randomly assigned to receive either zolpidem or a placebo starting two days before surgery and continuing for five days after surgery. The study uses a triple-blind design to monitor outcomes under controlled conditions. During the study, patients will complete various assessments including the Visual Analog Scale for pain, Oswestry Disability Index, Quality of Recovery questionnaire, Epworth Sleepiness Score, and Pain Catastrophizing Scale at multiple time points before and after surgery. Researchers will also track morphine use, hospital stay length, and any postoperative complications up to two years following surgery.
CONDITIONS
Brief Title
The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion
Research Team
P
Pui Yan, MS
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