Actively Recruiting
The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction
Led by Affiliated Hospital of Jiaxing University · Updated on 2026-01-14
60
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Exploring the 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction: The aim is to determine the optimal ventilation pressure for esophageal insufflation avoidance during anesthesia induction and to explore its guiding significance for anesthesia management. The goal is to provide a more precise and personalized ventilation pressure setting standard for clinical anesthesia, thereby enhancing the safety of the anesthesia induction phase.
CONDITIONS
Official Title
The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years, any gender
- ASA classification I to III
- Scheduled for elective general anesthesia surgery
- Body mass index (BMI) between 18.0 and 28.0 kg/m8
- Preoperative fasting: solid food more than 6 hours, liquids more than 2 hours
- Fewer than two criteria predicting difficult mask ventilation as defined by Langeron et al.
- No severe heart, lung, liver, or kidney diseases
- Signed informed consent and ability to follow the study protocol
You will not qualify if you...
- Pregnant or breastfeeding women
- History of upper gastrointestinal diseases such as gastroesophageal reflux disease, peptic ulcers, or hiatal hernia
- Recent respiratory infections or chronic cough within 2 weeks
- Need for emergency surgery or airway obstruction after anesthesia induction requiring urgent intubation
- Inability to maintain adequate oxygenation during mask ventilation (SpO2 < 92% for 30 seconds despite treatment)
- History of contraindications or allergies to study medications
- Inability to understand or unwillingness to cooperate with the study
- Presence of oropharyngeal or facial pathology
- Having an indwelling gastric tube or prior gastric surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Affiliated Hospital of Jiaxing University
Jiaxing, China
Actively Recruiting
Research Team
Q
Qinghe Zhou
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SEQUENTIAL
Primary Purpose
DIAGNOSTIC
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here