Actively Recruiting

Phase Not Applicable
Age: 15Years +
FEMALE
NCT05444504

Effectiveness and Acceptability of Insertable Devices for Obstetric Fistula Management

Led by University of California, San Francisco · Updated on 2025-12-22

100

Participants Needed

3

Research Sites

193 weeks

Total Duration

On this page

Sponsors

U

University of California, San Francisco

Lead Sponsor

K

Korle-Bu Teaching Hospital, Accra, Ghana

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators propose a clinical trial and nested qualitative study to 1) quantify the effectiveness of an insertable vaginal cup to manage fistula urinary incontinence, 2) examine user and implementer acceptability, and 3) quantify fistula management cost. Two intervention models will be compared among women awaiting fistula surgery or whose surgery was unsuccessful: 1) a vaginal cup ('cup'), and 2) the cup attached via rubber tubing to a leg-secured urine collection bag ('cup+') for greater urine holding capacity.

CONDITIONS

Official Title

Effectiveness and Acceptability of Insertable Devices for Obstetric Fistula Management

Who Can Participate

Age: 15Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female with vesicovaginal fistula confirmed by dye test and clinical exam at least 3cm from the urethral opening
  • Adequate vaginal capacity to accommodate the cup as determined by a physician
  • Willing to insert and remove the cup or cup+
  • Clear understanding of the study procedures
  • Willing to participate fully
  • Fistula not yet repaired or previous surgery failed, with at least 6 months since surgery
  • If previous fistula repair, at least 3 months post-delivery
  • If recent birth, age 18 years or older or an emancipated minor
  • Able to speak English or a local language
Not Eligible

You will not qualify if you...

  • Any rectovaginal fistula
  • Urinary leakage less than 6ml over 6 hours
  • Candidates for catheterization who could heal without surgery (less than 3 months post-delivery)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 3 locations

1

Mercy Women's Catholic Hospital

Mankessim, Ghana

Actively Recruiting

2

Tamale Fistula Center

Tamale, Ghana

Actively Recruiting

3

Gynocare Women's and fistula hospital

Eldoret, Kenya

Enrolling by Invitation

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Research Team

N

Nessa E Ryan, PhD

CONTACT

A

Alison M El Ayadi, ScD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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