Actively Recruiting
Effectiveness and Acceptability of the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in People With Long COVID-19.
Led by Instituto de Investigación Sanitaria Aragón · Updated on 2025-05-22
90
Participants Needed
2
Research Sites
87 weeks
Total Duration
On this page
Sponsors
I
Instituto de Investigación Sanitaria Aragón
Lead Sponsor
H
Hospital Royo Villanova de Zaragoza
Collaborating Sponsor
AI-Summary
What this Trial Is About
This Randomized Controlled Trial (RCT) aims to assess the effectiveness and acceptability of the Unified Protocol (UP) in an online group format for the treatment of emotional disorders in adults. Participants will be 90 adults (45 in the control group and 45 in the experimental group) with diagnosis of long COVID and comorbid emotional disorders. Participants will be recruited at Hospital Royo Villanova from Zaragoza, Spain. In this study it will be explored whether the changes obtained after the intervention in emotional disorders and cognitive complaints are maintained over 12 months. Additionally, levels of chronic stress will be longitudinally evaluated in the experimental group through accumulated cortisol levels in hair, before and after the application of the UP.
CONDITIONS
Official Title
Effectiveness and Acceptability of the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in People With Long COVID-19.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Residing in Autonomous Community of Aragon (Spain).
- Being at least 18 years old.
- Understanding of Spanish.
- Diagnosed with long COVID-19: documented SARS-CoV-2 infection with symptoms persisting beyond 12 weeks after acute infection.
- Symptoms of depression (ODSIS67) and/or anxiety (OASIS68).
- Meeting criteria for an emotional disorder diagnosis.
- Having access to Internet.
- Signing the informed consent.
You will not qualify if you...
- Pre-existing emotional symptoms prior to acute SARS-CoV-2 infection.
- Currently receiving psychological treatment.
- Having a diagnosis of severe mental disorder (e.g., personality disorder, bipolar disorder).
- Active suicidal ideation at time of assessment.
- Individuals on psychotropic medication must maintain their dosage throughout the study unless medically contraindicated.
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Hospital Royo Villanova
Zaragoza, Zaragoza, Spain, 50015
Not Yet Recruiting
2
Hospital Royo Villanova
Zaragoza, Spain
Actively Recruiting
Research Team
J
Jorge Osma Jorge Osma, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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