Comparing Chlorzoxazone and Orphenadrine Citrate for Treating Orofacial Pain in Bruxism Patients

What this Trial Is About

Researchers are evaluating the clinical effectiveness of chlorzoxazone compared to orphenadrine citrate for relieving orofacial pain in people who grind their teeth bruxism. The study is a randomized clinical trial involving 60 patients over 15 years old who have orofacial and temporomandibular pain but no chronic systemic illnesses. The goal is to assess how well each drug reduces pain severity and improves temporomandibular joint function. Participants are randomly assigned to one of two groups one group receives chlorzoxazone twice daily for two weeks, while the other group receives orphenadrine citrate on the same schedule. Both treatments are taken orally. Pain severity is measured using the Visual Analogue Scale VAS at the start, after 7 days, and after 14 days. A temporomandibular joint evaluation form is also used before and after treatment to assess joint parameters. During the study, participants will undergo pain assessments and joint evaluations at specified intervals. Researchers will monitor changes in orofacial pain scores from baseline to the end of treatment at two weeks. Statistical analysis will be conducted to compare the effects of the two drugs. The study is sponsored by the University of Baghdad and aims to provide detailed information on managing bruxism-related pain.

Effectiveness of Chlorzoxazone Versus Orphenadrine Citrate in Alleviating Bruxism Pain