Actively Recruiting
Effectiveness of Chlorzoxazone Versus Orphenadrine Citrate in Alleviating Bruxism Pain
Led by University of Baghdad · Updated on 2025-08-07
60
Participants Needed
1
Research Sites
5 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To evaluate the clinical effectiveness of chlorzoxazone in comparison to orphenadrine Citrate in relieving the orofacial pain in bruxers. Subjects and Methods: 60 patients above 15-years old complaining of orofacial and temporomandibular disorder/pain, with no history of chronic systemic illness, will be recruited. Patients will randomly be allocated into two groups (n=30): the first group will receive Relaxon (chlorzoxazone) twice daily for two weeks, while the second group will receive Norgesic (orphenadrine Citrate) twice daily for two weeks as well. Pain severity will be assessed by Visual Analogue Scale (VAS) at day 0, 7, and day 14. In addition, a temporomandibular joint (TMJ) evaluation form will be utilized to assess the TMJ parameters before and after initiation of the treatment protocol, i.e at 0 and 14 days. Non parametric statistical analysis will be conducted to explain the results using SPSS V29.
CONDITIONS
Official Title
Effectiveness of Chlorzoxazone Versus Orphenadrine Citrate in Alleviating Bruxism Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged above 15 years-old complaining of orofacial and temporomandibular disorder/pain.
- Patients with no history of chronic systemic illness.
You will not qualify if you...
- Patients with orofacial injuries.
- Patients with head injuries.
- Patients taking analgesics for the last 14 days.
AI-Screening
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Trial Site Locations
Total: 1 location
1
College of Dentistry
Baghdad, Iraq
Actively Recruiting
Research Team
N
Noor R. Al-Hasani, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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