Evaluating Coenzyme Q10 Toothpaste With or Without Probiotics to Improve Gum Health in Pregnant Women Undergoing Periodontal Therapy

What this Trial Is About

Researchers are evaluating the effectiveness of adding coenzyme Q10 and probiotic supplements Limosilactobacillus reuteri Prodentis4 to non-surgical periodontal therapy in pregnant women. The goal is to see if this combined approach can improve oral health by balancing the oral microbiota and reducing dental plaque and gum inflammation during pregnancy. This randomized controlled trial involves 40 pregnant participants. Participants are divided into two groups. The test group receives professional oral hygiene every three months, uses a coenzyme Q10-based toothpaste twice daily, and takes a daily probiotic tablet for six months. The control group follows the same oral hygiene and toothpaste routine but does not take probiotics. Additional hygiene tools such as soft picks and a sonic toothbrush are used by all participants. During the six-month study, researchers will assess dental plaque reduction using the Plaque Index at baseline, 1, 3, and 6 months. Other measures include bleeding on probing, pocket depth, clinical attachment level, gingival inflammation, plaque distribution, and gingival recession. Participants will be monitored for compliance and periodontal health changes to determine the impact of the combined treatment.

Effectiveness of Coenzyme Q10 and Probiotics in Periodontal Therapy During Pregnancy