Actively Recruiting
Effectiveness of Cognitive Stimulation Treatment in Patients With Parkinson's Disease
Led by Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · Updated on 2024-03-21
68
Participants Needed
1
Research Sites
310 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to evaluate the relationship between GBA mutation and cognitive stimulation treatment response in patients with Parkinson's disease. The main questions it aim to answer are: • assess whether the GBA mutation is associated with greater or lesser response to cognitive training treatment compared to a control group of PD patients without genetic mutations. • investigate the effect of cognitive stimulation program on behavioural aspects as secondary consequence induced by the possible improvement of cognitive abilities following treatment. Participants will be undergo to: - a neuropsychological evaluation describing their cognitive profile; - a genetic investigation and finally included in a cognitive stimulation programs according to regular clinical practice. Researchers will compare PD patients with GBA mutation and patients without genetic mutation to evaluate the effectiveness of cognitive stimulation treatment.
CONDITIONS
Official Title
Effectiveness of Cognitive Stimulation Treatment in Patients With Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with Parkinson's disease according to the Gelb et al. criteria
- Patients who have carried out genetic screening for MP
- Patients who have a raw score in the range 15.50 to 22.23 at Montreal cognitive assessment (MoCA)
- Patients who have signed the informed consent and the Privacy Policy
- Patients who are included in cognitive stimulation programs according to regular clinical practice
You will not qualify if you...
- Patients with the initial suspicion of MP that during the diagnostic work-up they were suffering from a different pathology
- Patients who have refused consent to participate in the study
- Patients with a diagnosis of MP and cognitive profile of dementia
- Patients undergoing deep brain neurostimulation (DBS-STN) treatment. Patients treated with DBS-STN were excluded because such treatment involves a surgical procedure whose effects on cognitive functioning could represent an interfering variable.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy
Actively Recruiting
Research Team
F
Fabiana Ruggiero, MSc in Psychology
CONTACT
F
Francesca Mameli, MSc in Psychology
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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