Actively Recruiting
Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards
Led by Universitat Internacional de Catalunya · Updated on 2026-03-16
40
Participants Needed
1
Research Sites
217 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized, double-blind, split-mouth clinical trial evaluates the effectiveness of at-home dental bleaching using customized nightguards fabricated by digital (3D-printed CAD-CAM) and conventional methods, with and without reservoirs. Adult participants with good general and oral health and a baseline tooth shade of A2 or darker undergo bleaching with 10% carbamide peroxide. Outcomes include tooth color change (subjective and spectrophotometric measures), tooth sensitivity, gingival irritation, patient comfort, and patient satisfaction over time.
CONDITIONS
Official Title
Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Good general and oral health
- No current medical treatment (self-reported)
- No need for surgical, endodontic, periodontal, or restorative dental treatment
- At least six upper and six lower anterior teeth free of caries and restorations
- Maxillary central incisors with baseline shade A2 or darker
- Willingness to follow the study protocol and use the study-provided oral hygiene products/instructions
You will not qualify if you...
- Previous tooth bleaching treatment
- Orthodontic appliances or prostheses that interfere with treatment
- Severe intrinsic discoloration such as tetracycline staining, fluorosis, or discolored endodontically treated teeth
- Pregnancy or lactation
- Bruxism
- Gingival recession, dentin exposure, visible enamel cracks, or other conditions linked to increased sensitivity
- Use of anti-inflammatory or analgesic medication during the study period
AI-Screening
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Trial Site Locations
Total: 1 location
1
Clínica Universitària d'Odontologia UIC Barcelona
Sant Cugat del Vallès, BARCELONA, Spain, 08195
Actively Recruiting
Research Team
M
MARTA VALLES, DDS, PhD
CONTACT
L
LISSETHE PEÑATE, DDS, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
TREATMENT
Number of Arms
4
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