Evaluating Dexmedetomidine with Bupivacaine for Pain Relief in Children Undergoing Open Appendectomy with General Anesthesia

What this Trial Is About

Researchers are evaluating whether adding dexmedetomidine to bupivacaine in a caudal block can provide longer and better pain relief for children aged 2 to 7 years undergoing open appendectomy surgery. The study also aims to assess the effect of this combination on recovery quality, including the rate of emergence delirium, as well as overall safety. Children in the study will be randomly assigned to one of two groups. One group will receive a single-shot caudal block with 1 mLkg of 0.25% bupivacaine mixed with 1 mL of normal saline. The other group will receive a similar caudal block but with bupivacaine mixed with 1 gkg of dexmedetomidine diluted in 1 mL of normal saline. All treatments are given under general anesthesia during the surgery. Participants will be monitored for up to 24 hours after the caudal block to measure the time until the first need for additional pain relief. Researchers will also observe recovery quality and any side effects. The study involves careful safety monitoring throughout the post-operative period to assess how well children recover and manage pain after surgery.

The Effectiveness of Dexmedetomidine as an Adjuvant for Bupivacaine Caudal Block in Pediatric Open Appendectomy Under General Anesthesia