Actively Recruiting

Phase Not Applicable
Age: 2Years - 7Years
All Genders
NCT07088900

The Effectiveness of Dexmedetomidine as an Adjuvant for Bupivacaine Caudal Block in Pediatric Open Appendectomy Under General Anesthesia

Led by Ain Shams University · Updated on 2026-05-06

60

Participants Needed

1

Research Sites

51 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate if adding dexmedetomidine to bupivacaine in a caudal block can provide longer and better quality pain relief for children after open appendectomy surgery. The study will also assess the effect of this combination on the quality of recovery, including the incidence of emergence delirium, and its overall safety profile.

CONDITIONS

Official Title

The Effectiveness of Dexmedetomidine as an Adjuvant for Bupivacaine Caudal Block in Pediatric Open Appendectomy Under General Anesthesia

Who Can Participate

Age: 2Years - 7Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children aged 2 to 7 years
  • ASA physical status I or II
  • Written informed consent given by legal guardian
Not Eligible

You will not qualify if you...

  • Legal guardian refuses participation
  • Allergy or hypersensitivity to local anesthetics or dexmedetomidine
  • Coagulation disorder or use of anticoagulant therapy
  • Active infection near the injection site
  • Significant anatomical abnormalities of the lumbosacral spine
  • Pre-existing neurological or psychiatric disorders or history of convulsions
  • Surgery expected to last longer than 2.5 hours
  • Severe asthma or active wheezing

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ain Shams university hospitals

Cairo, Egypt

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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The Effectiveness of Dexmedetomidine as an Adjuvant for Bupivacaine Caudal Block in Pediatric Open Appendectomy Under General Anesthesia | DecenTrialz