Actively Recruiting

Phase Not Applicable
Age: 10Years - 12Years
All Genders
Healthy Volunteers
NCT06267989

The Effectiveness of Early Intervention to Correct the Position of PDC:s

Led by Göteborg University · Updated on 2025-04-24

324

Participants Needed

3

Research Sites

169 weeks

Total Duration

On this page

Sponsors

G

Göteborg University

Lead Sponsor

U

University of Sheffield

Collaborating Sponsor

AI-Summary

What this Trial Is About

Approximately 2-3% of children will have problems with one or both of their permanent or 'adult' canine teeth in the upper jaw. These canine teeth sometimes fail to erupt properly, because they are displaced into the roof of the mouth or palate. These are known as palatally displaced canines, PDC, (Brin et al., 1986, Ericson and Kurol, 1987). In addition to failing to erupt, displaced teeth can cause problems, such as damage to the roots or displacement of the neighbouring teeth (Ericson and Kurol, 1988a, Ericson and Kurol, 2000, Falahat et al., 2008). It has been suggested that if the primary ('baby' or 'milk') canine is extracted at an appropriate time in a child with a suspected palatally displaced canine, then the displaced tooth might spontaneously correct its position (Ericson and Kurol, 1988b) and the extraction of the baby canine when a clinician suspects that the adult canine is displaced has become accepted clinical practice (Short, 2009). This appears to be on the basis of one report of a series of 35 children who received the intervention and no control group (Ericson and Kurol, 1988b). Two recent systematic reviews have examined the evidence for the effectiveness of removal of the primary canine with the aim of correcting the eruption path of a palatally displaced canine. A recent systematic review published in The Cochrane Library in 2021 (Benson et al., 2021) noted that the evidence for any intervention to correct the eruption path of a displaced permanent canine is weak and further research is required. Numerous problems with the reported studies were identified by both reviews. Other authors have suggested that using a RME (Rapid Maxillary expansion) or headgrear (EOT) to create sufficient space within the dental arch for the permanent canine tooth will encourage the tooth to erupt (Baccetti et al., 2011). This approach might be less traumatic to a child who may have had no experience of dental treatment, other than routine check-ups. If either or both approaches are shown to be effective then their widespread use would be advantageous to both the child and the healthcare provider, because the need for an operation, under general anaesthetic, to uncover the tooth and extensive brace treatment to straighten the tooth will be avoided.

CONDITIONS

Official Title

The Effectiveness of Early Intervention to Correct the Position of PDC:s

Who Can Participate

Age: 10Years - 12Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Children aged 10 to 12 years
  • One or both upper permanent canine teeth are not palpable or erupt unevenly
  • Dental X-rays confirm the permanent canine tooth is displaced towards the palate
  • Canines located outside sector 5 (excluded from trial)
Not Eligible

You will not qualify if you...

  • Buccal displacement of the canine teeth
  • Missing permanent lateral incisors
  • Severe dental crowding in the upper arch (more than 2 mm in any affected quadrant)
  • Associated dental pathology

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Private practice

Traben-Trarbach, Germany

Not Yet Recruiting

2

Gothenbrug University

Gothenburg, Sweden

Actively Recruiting

3

University of Sheffield

Sheffield, United Kingdom

Not Yet Recruiting

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Research Team

F

Farhan Bazargani, DDS, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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