Survey of Perioperative Practices in Gastric Cancer Surgery for Establishing an Enhanced Recovery After Surgery Program Across 10 Tertiary Hospitals in South Korea.
Ho-Jin Lee, Jeesun Kim, Bon-Wook Koo...
https://pubmed.ncbi.nlm.nih.gov/40631472Actively Recruiting
Phase Not Applicable
Age: 19Years +
All Genders
ID06984952
Effectiveness of Enhanced Recovery After Surgery (ERAS) on Postoperative Recovery After Minimally Invasive Gastrectomy: A Multi-center Open-labeled Randomized Controlled Study
Led by Seoul National University Hospital · Updated on 2025-09-05
308
Participants Needed
10
Research Sites
12 weeks
Total Duration
On this page
Sponsors
S
Seoul National University Hospital
Lead Sponsor
S
Seoul National University Bundang Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating the impact of an Enhanced Recovery After Surgery (ERAS) protocol on recovery following minimally invasive gastrectomy in adults with gastric cancer. This prospective, randomized, open-label, multicenter study compares the ERAS protocol to conventional perioperative care to see if more patients meet discharge criteria earlier after surgery. The study aims to improve post-surgery recovery and reduce hospital stays by using evidence-based practices. Participants are randomly assigned to either the ERAS group or the conventional care group. The ERAS protocol includes preoperative carbohydrate loading, shorter fasting periods, multimodal opioid-sparing pain relief, early removal of drains and intravenous lines, early mobilization, and prevention of nausea and vomiting. The conventional group receives the current standard care at the institution. Both groups undergo minimally invasive gastrectomy, either laparoscopic or robotic. During the study, patients are monitored for meeting discharge criteria at 9:00 AM on postoperative day 4. Researchers also assess pain levels, gastrointestinal function, nausea and vomiting, quality of recovery using the EQ-5D-5L questionnaire, and major postoperative complications up to 30 days after surgery. Patients provide feedback through questionnaires, and their health is closely followed to evaluate the benefits of the ERAS protocol compared to conventional care.
CONDITIONS
Brief Title
Effectiveness of ERAS on Postoperative Recovery After Minimally Invasive Gastrectomy
Who Can Participate
Age: 19Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Adults aged 19 years or older scheduled for elective laparoscopic or robotic gastrectomy for gastric cancer
- American Society of Anesthesiologists physical status classification I to III
- Ability to provide written informed consent and complete patient-reported outcome measures
You will not qualify if you...
- Need for resection of organs other than the stomach during surgery (except gallbladder removal)
- History of upper abdominal surgery (except gallbladder removal)
- Known allergy to fentanyl, ropivacaine, acetaminophen, or non-steroidal anti-inflammatory drugs
- Deemed unsuitable for study participation by investigators
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Surgery and Immediate Post-operative Care
Duration - Hospital stay until discharge, typically around 4 days post-surgery
Participants undergo minimally invasive gastrectomy followed by immediate postoperative care according to either the ERAS protocol or conventional care.
Daily hospital visits during postoperative stay
Post-operative Follow-up
Duration - Up to 30 days postoperatively
Participants are monitored for recovery outcomes including pain, gastrointestinal function, nausea and vomiting, quality of recovery, and complications up to 30 days after surgery.
Assessments at 2, 24, 48, 72, and 96 hours post-surgery and follow-up visits up to 30 days
Trial Site Locations
Total: 10 locations
1
Pusan National University Hospital
Busan, South Korea
Not Yet Recruiting
2
Dongsan Hospital, Keimyung University School of Medicine
Daegu, South Korea
Actively Recruiting
3
Chungnam National University Hospital
Daejeon, South Korea
Not Yet Recruiting
4
National Cancer Center
Goyang, South Korea
Not Yet Recruiting
5
Seoul National University Bundang Hospital
Seongnam, South Korea
Not Yet Recruiting
6
Seoul National University Hospital
Seoul, South Korea
Actively Recruiting
7
Seoul St. Mary's Hospital
Seoul, South Korea
Not Yet Recruiting
8
Severance hospital
Seoul, South Korea
Not Yet Recruiting
9
SMG-SNU Boramae Medical Center,
Seoul, South Korea
Not Yet Recruiting
10
Ajou University School of Medicine
Suwon, South Korea
Not Yet Recruiting
Loading map...
Research Team
H
Hojin Lee, MD, PhD
D
Do Joong Park, MD, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Published Research Related To This Trial
Effectiveness of ERAS program on postoperative recovery after gastric cancer surgery: a randomized clinical trial.
Ho-Jin Lee, Jeesun Kim, Soo-Hyuk Yoon...
https://pubmed.ncbi.nlm.nih.gov/40072360