Effectiveness and Cost Evaluation of Different Endovascular Treatments for Arteriovenous Graft Fistula Failure in Hemodialysis Patients

What this Trial Is About

Researchers are studying patients with arteriovenous graft fistula failure who require hemodialysis. This real-world, prospective study aims to evaluate the effects and health economic value of different endovascular treatment methods for this condition. The study focuses on lesions in the inflow tract, middle segment, and outflow vein of the dialysis pathway. A total of 240 patients will be recruited from a single center between September 2023 and December 2024 to compare various treatment approaches. Participants will receive different types of endovascular therapy, including simple balloon dilation, cutting balloon dilation, drug-coated balloon dilation, and stent implantation. Treatments are performed through the arterial end of the anastomosis to open the target lesion, with additional approaches if initial attempts fail. Patients are grouped based on the treatment method used, and treatments are selected according to the lesions characteristics. During the study, patients will be monitored for technical success, major adverse events during the perioperative period, and symptom-driven re-intervention rates at 1, 6, 12, 18, and 24 months after treatment. Researchers will also track target vessel patency rates and total hospital costs related to the target lesions. Participants will provide informed consent and agree to follow-up visits at specific time points throughout the 24-month follow-up period.

Effectiveness and Health Economics of Endoluminal Treatment of Arteriovenous Graft Fistula.