Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07324746

The Effectiveness of a Herbal Supplement in Osteoarthritis.

Led by Middlesex University · Updated on 2026-01-29

30

Participants Needed

1

Research Sites

38 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the effectiveness and safety of a combined herbal supplement containing Boswellia serrata, Curcuma longa, and Vitis vinifera in adults with clinically diagnosed knee or hip osteoarthritis. The primary objective is to determine whether the supplement improves osteoarthritis-related symptoms. The supplement will be compared with a placebo. Participants will: * take the supplement and placebo for 4 weeks each, one at a time; * complete validated questionnaires (6 times online) * perform three performance-based physical tests (6 times online) * provide a urine sample

CONDITIONS

Official Title

The Effectiveness of a Herbal Supplement in Osteoarthritis.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18 years or older
  • Diagnosis of osteoarthritis in knee or hip
  • Pain score of at least 4 on Numerical Rating Scale during most painful movement in last 24 hours
  • Lequesne's Functional Index score of 7 or higher
  • Able to walk and move around without assistance
Not Eligible

You will not qualify if you...

  • Pregnant or breastfeeding
  • Autoimmune diseases such as rheumatoid arthritis, gout, or lupus
  • Joint trauma, injury, infection, meniscus tear, or complete loss of articular cartilage
  • Expectation of surgery
  • History of viscous or corticosteroid injections into affected joints or oral corticosteroids within last 12 months
  • Allergy to intervention ingredients or NSAIDs
  • Peptic ulceration or upper gastrointestinal bleeding
  • High alcohol intake, substance abuse, or history of addiction
  • Tumor or cancer
  • Abnormal kidney or liver function or altered blood chemistry
  • Use of medications that may interfere with the study interventions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Middlesex Univeristy London

London, United Kingdom, NW4 4BT

Actively Recruiting

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Research Team

P

Patrycja Brodka Pedrp, MSc

CONTACT

L

Lygeri Dimitriou, Dr

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

OTHER

Number of Arms

2

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The Effectiveness of a Herbal Supplement in Osteoarthritis. | DecenTrialz