Actively Recruiting
Effectiveness-Implementation Evaluation of Acute Kidney Injury Decision Support
Led by Johns Hopkins University · Updated on 2026-04-20
200000
Participants Needed
1
Research Sites
246 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
A
Agency For Healthcare Research & Quality
Collaborating Sponsor
AI-Summary
What this Trial Is About
Study Purpose: This study is testing an artificial intelligence (AI)-powered clinical decision support (CDS) system designed to help emergency department (ED) doctors detect and manage acute kidney injury (AKI) earlier. The goal is to see whether the tool improves patient care, clinician decision-making, and hospital outcomes when used in real-world ED settings. Study Design: The AI tool will be gradually introduced at three hospital EDs: Johns Hopkins Hospital (JHH) Bayview Medical Center (BMC) Howard County General Hospital (HCGH) Before the tool is activated, it will run in the background to collect baseline data without influencing care. Once implemented, doctors will receive training, and researchers will track how often the tool is used and whether it improves AKI care. What the Study Measures: Process Outcomes: Does the tool help doctors identify AKI sooner, avoid harmful medications, and improve decision-making about hospitalization? Clinical Outcomes: Does the tool reduce the number and severity of AKI cases and improve kidney-related health outcomes? Implementation Outcomes: Do ED doctors find the tool useful? Does it fit into the ED doctor's workflow without slowing the ED doctor's down? Expected Impact: If successful, the AI tool could be expanded to other hospitals and used to improve early detection and treatment of AKI, reducing kidney complications and improving patient care nationwide.
CONDITIONS
Official Title
Effectiveness-Implementation Evaluation of Acute Kidney Injury Decision Support
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients visiting the emergency department at Johns Hopkins Hospital, Bayview Medical Center, or Howard County General Hospital
- At least one serum creatinine test performed during the emergency department visit
- Adults aged 18 years or older at the time of the emergency department visit
- Availability of follow-up creatinine measurement within 72 hours for analysis of new or progressive AKI
You will not qualify if you...
- No serum creatinine measurement taken during the emergency department visit
- Discharged patients without follow-up serum creatinine test within 72 hours
- Age below 18 years
- History of end-stage kidney disease or receiving chronic dialysis (hemodialysis or peritoneal dialysis)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Johns Hopkins Hospital
Baltimore, Maryland, United States, 21287
Actively Recruiting
Research Team
E
Eili Y Klein, PhD
CONTACT
M
Michael Ehmann, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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