Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07587190

Effectiveness of Implementing the Adapted Practice Guidelines for Primary Care of Acute Abdomen in Zambia: An Effectiveness-Implementation Hybrid Type 2 Study Design

Led by University of Bergen · Updated on 2026-05-14

280

Participants Needed

1

Research Sites

121 weeks

Total Duration

On this page

Sponsors

U

University of Bergen

Lead Sponsor

U

University of Zambia

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are studying how adapting and implementing practice guidelines for acute abdomen at the primary care level in Zambia can affect patient care. The study uses a mixed method approach, combining qualitative and quantitative data from healthcare workers to modify guidelines originally developed for high-income countries to fit a low- and middle-income context. The main goal is to see if these adapted guidelines can reduce hospital stay length and improve outcomes for patients with acute abdomen. The study compares two sites: an intervention site where the adapted acute abdomen guidelines will be put into practice, and a control site where no new guidelines will be introduced. This allows researchers to evaluate the effect of guideline implementation on patient management. The intervention site will follow specific adjusted guidelines tailored for acute abdomen care at the primary level. Participants in the study include all patients aged 18 and older presenting with acute abdomen, except those with trauma-related cases or immediate postoperative patients from other facilities. Data collection will focus on length of hospital stay as the primary outcome measured over 7 days. The study is designed to improve management capacity at primary care and may help reduce morbidity and mortality associated with acute abdomen in this setting. The study is sponsored by the University of Bergen and runs from September 2025 through December 2028.

CONDITIONS

Brief Title

Effectiveness of Implementing the Adapted Practice Guidelines for Primary Care of Acute Abdomen in Zambia: An Effectiveness-Implementation Hybrid Type 2 Study Design.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients 18 years and older with acute abdomen, including surgical, gynecological, and medical causes, managed at the intervention or control site during the study period
Not Eligible

You will not qualify if you...

  • Acute abdomen cases caused by trauma
  • Immediate postoperative patients operated on at other facilities presenting with acute abdomen

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Up to the study period duration

Participants at the intervention site receive care following the newly implemented adapted practice guidelines for acute abdomen, while participants at the control site receive standard care without guideline implementation.

Visits as part of routine care during hospital stay

Monitoring

Duration - Up to 7 days post hospital admission

Participants are observed for outcomes such as length of hospital stay and recovery following the care received.

Follow-up visits during hospital stay

Trial Site Locations

Total: 1 location

1

Kanyama First Level Hospital and Matero First Level Hospital

Lusaka, Lusaka Province, Zambia, 10101

Actively Recruiting

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Research Team

W

Wilson Mbewe, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

Frequently Asked Questions

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