Actively Recruiting
Effectiveness of the Journey Total Knee Arthroplasty Versus Two Standard of Care Total Knee Arthroplasty Prostheses
Led by University of Alberta · Updated on 2025-07-09
75
Participants Needed
1
Research Sites
429 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of the study is to determine if knee replacement performed using Journey II implant is different from two other standard-of-care knee replacements using Stryker and Zimmer in terms of knee movements and forces, walking patterns, pain, and function after surgery.
CONDITIONS
Official Title
Effectiveness of the Journey Total Knee Arthroplasty Versus Two Standard of Care Total Knee Arthroplasty Prostheses
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed an approved informed consent form
- Male or non-pregnant female aged 50 to 75 years at time of device implantation
- Diagnosis of non-inflammatory degenerative joint disease
- Candidate for primary posterior-stabilized total knee replacement
- Willing and able to comply with postoperative clinical, radiographic evaluations, and rehabilitation
You will not qualify if you...
- Body Mass Index (BMI) of 40 kg/m2 or higher
- Varus or valgus deformity greater than 15 degrees, flexion contracture over 20 degrees, or knee flexion range of motion less than 90 degrees in either leg
- Active or suspected latent infection in or around the affected knee at time of implantation
- Orthopaedic surgery to lower extremities within past 6 months or expected within next year (other than this knee replacement)
- Requires bilateral total knee replacements or had contralateral partial or total knee replacement within past 6 months
- Other medical conditions limiting safety and efficacy evaluation
- Requires revision surgery of a previous knee replacement or knee fusion
- Known sensitivity to device materials
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Edmonton Bone and Joint Centre
Edmonton, Alberta, Canada, T5E 5R8
Actively Recruiting
Research Team
A
Ailar Ramadi, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
3
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