Efficacy of periodontal plastic surgery procedures in the treatment of localized facial gingival recessions. A systematic review.
Francesco Cairo, Michele Nieri, Umberto Pagliaro
https://pubmed.ncbi.nlm.nih.gov/24641000/Actively Recruiting
Led by Göteborg University · Updated on 2025-03-13
30
Participants Needed
1
Research Sites
30 weeks
Total Duration
This research aims to evaluate treatment outcomes for multiple adjacent gingival recession defects MAGRD using a modified coronally advanced tunnel technique MCAT with two types of connective tissue grafts conventional connective tissue grafts CTG and micro connective tissue grafts micro-CTG. Gingival recession involves exposure of the tooth root due to gum margin displacement. The study compares the effectiveness and predictability of micro-CTGs against conventional CTGs over a 1-year period, focusing on root coverage and patient satisfaction, while also assessing morbidity shortly after surgery. Participants will undergo mucogingival surgery where either a conventional CTG harvested from the palate or multiple micro-CTGs prepared from a harvested graft will be placed on the recipient site and sutured to cover multiple adjacent recession defects. The surgical method used is a modified coronally advanced tunnel. The study includes a control group receiving conventional CTG and a test group receiving micro-CTGs. The follow-up period for outcomes extends up to 1 year, with morbidity evaluated up to 2 weeks post-surgery. During the study, participants will be monitored for root coverage success using measures such as mean mid-facial recession coverage, complete root coverage, changes in keratinized tissue width, and gingival thickness. Patient morbidity is assessed within the first two weeks after surgery, and patient satisfaction is evaluated over the 1-year follow-up. The study involves randomized assignment to groups and triple masking to reduce bias, with participation lasting at least one year.
CONDITIONS
Effectiveness of Micro Connective Tissue Graft for Treatment of Multiple Adjacent Gingival Recession Defects
O
Olivier Carcuac, DDS, PhD
J
Jan Derks, DDS, PhD
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Göteborg University
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single surgical procedure with follow-up lasting up to 2 weeks
Participants undergo mucogingival surgery using either conventional connective tissue graft or multiple micro connective tissue grafts to cover multiple adjacent gingival recession defects.
1 surgery visit and several follow-up visits for up to 2 weeks
Duration - Up to 1 year
Participants are monitored for treatment outcomes including root coverage, tissue changes, patient morbidity, and satisfaction over a period of up to 1 year.
Periodic visits for outcome assessments up to 12 months
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Francesco Cairo, Michele Nieri, Umberto Pagliaro
https://pubmed.ncbi.nlm.nih.gov/24641000/Francesco Cairo
https://pubmed.ncbi.nlm.nih.gov/28758301/Filippo Graziani, Stefano Gennai, Silvia Roldán...
https://pubmed.ncbi.nlm.nih.gov/24641002/Vincent Ronco, Michel Dard
https://pubmed.ncbi.nlm.nih.gov/27525096/Maurizio S Tonetti, Søren Jepsen, Working Group 2 of the European Workshop on Periodontology
https://pubmed.ncbi.nlm.nih.gov/24640999/Göteborg University
Lead Sponsor