Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
ID06030947

Tunnel Surgery Combined With a Micro Connective Tissue Graft for the Treatment of Multiple Adjacent Gingival Recession Defects: a Multi-center Randomized Controlled Clinical Trial.

Led by Göteborg University · Updated on 2025-03-13

30

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate treatment outcomes for multiple adjacent gingival recession defects (MAGRD) using a modified coronally advanced tunnel technique (MCAT) with two types of connective tissue grafts: conventional connective tissue grafts (CTG) and micro connective tissue grafts (micro-CTG). Gingival recession involves exposure of the tooth root due to gum margin displacement. The study compares the effectiveness and predictability of micro-CTGs against conventional CTGs over a 1-year period, focusing on root coverage and patient satisfaction, while also assessing morbidity shortly after surgery. Participants will undergo mucogingival surgery where either a conventional CTG harvested from the palate or multiple micro-CTGs prepared from a harvested graft will be placed on the recipient site and sutured to cover multiple adjacent recession defects. The surgical method used is a modified coronally advanced tunnel. The study includes a control group receiving conventional CTG and a test group receiving micro-CTGs. The follow-up period for outcomes extends up to 1 year, with morbidity evaluated up to 2 weeks post-surgery. During the study, participants will be monitored for root coverage success using measures such as mean mid-facial recession coverage, complete root coverage, changes in keratinized tissue width, and gingival thickness. Patient morbidity is assessed within the first two weeks after surgery, and patient satisfaction is evaluated over the 1-year follow-up. The study involves randomized assignment to groups and triple masking to reduce bias, with participation lasting at least one year.

CONDITIONS

Brief Title

Effectiveness of Micro Connective Tissue Graft for Treatment of Multiple Adjacent Gingival Recession Defects

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Systemically healthy
  • Having between 4 and 6 adjacent RT1/RT2 gingival recession defects on the upper or lower jaw
  • Each recession defect has a depth of at least 2 mm
  • Full-mouth plaque score less than 20%
  • Full-mouth bleeding score less than 20%
Not Eligible

You will not qualify if you...

  • Pregnancy or breastfeeding
  • Tobacco smoking
  • Uncontrolled medical conditions
  • Taking medication that may affect gum health
  • Having a thick gum tissue phenotype
  • Severe misalignment of teeth
  • Uncorrected trauma from toothbrushing
  • Previous root coverage surgeries
  • Presence of furcation defects (bone loss between roots of teeth)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Single surgical procedure with follow-up lasting up to 2 weeks

Participants undergo mucogingival surgery using either conventional connective tissue graft or multiple micro connective tissue grafts to cover multiple adjacent gingival recession defects.

1 surgery visit and several follow-up visits for up to 2 weeks

Follow-up

Duration - Up to 1 year

Participants are monitored for treatment outcomes including root coverage, tissue changes, patient morbidity, and satisfaction over a period of up to 1 year.

Periodic visits for outcome assessments up to 12 months

Trial Site Locations

Total: 1 location

1

Confident Dubai Palm

Dubai, United Arab Emirates, 0000

Actively Recruiting

Loading map...

Research Team

O

Olivier Carcuac, DDS, PhD

J

Jan Derks, DDS, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Similar Trials

Three-Dimensional Digital Evaluation of Soft Tissue Changes ...

Gingival Recession, Localized

Actively Recruiting

1 location

Clinical Evaluation of Tunneled Coronally Advanced Flap Vers...

Gingival Recession, Localized

Actively Recruiting

1 location

Comparing Coronally Advanced Flap and Tunneled Coronally Adv...

Gingival Recession Generalized Moderate

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Published Research Related To This Trial

Clinical efficacy of periodontal plastic surgery procedures: consensus report of Group 2 of the 10th European Workshop on Periodontology.

Maurizio S Tonetti, Søren Jepsen, Working Group 2 of the European Workshop on Periodontology

https://pubmed.ncbi.nlm.nih.gov/24640999

Efficacy of periodontal plastic surgery procedures in the treatment of localized facial gingival recessions. A systematic review.

Francesco Cairo, Michele Nieri, Umberto Pagliaro

https://pubmed.ncbi.nlm.nih.gov/24641000