Actively Recruiting
The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel.
Led by King Abdullah University Hospital · Updated on 2026-01-23
36
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
Sponsors
K
King Abdullah University Hospital
Lead Sponsor
J
Jordan University of Science and Technology
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel. The main questions it aims to answer are: * Does NBF gel enhance wound healing after graft harvesting from the palate? * Does NBF gel reduce the number of inflammatory mediators after surgery? * Does NBF gel reduce pain and discomfort at the palatal donor site? Researchers will compare NBF gel to a placebo (a look-alike gel that does not contain the active ingredients) to see if NBF gel enhances wound healing. Study steps include: * Participants will apply the assigned gel on the surgical wound 4 times a day for 4 weeks. * Clinical photographs and measurements will be obtained on days (0, 1, 2, 4, 7, 15, 21, 30). * Wound fluid samples will be collected on days (0, 1, 2, 4, 7). * Participants will be asked about the level of pain and analgesic consumption on each follow-up visit.
CONDITIONS
Official Title
The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with gingival recession indicated for root coverage or phenotype modification
- 18 years or older
- No systemic disease
- Non-smoker
- No use of antibiotics, corticosteroids, anti-inflammatory medication, or hormones in the past 3 months
You will not qualify if you...
- Pregnant or lactating women
- Patients with immune or systemic diseases
- Allergy to any ingredient in the gel
AI-Screening
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Trial Site Locations
Total: 1 location
1
Jordan University of Science and Technology, Faculty of Dentistry
Irbid, Irbid Governorate, Jordan, 22110
Actively Recruiting
Research Team
L
Lana Bader, DClinDent Perio
CONTACT
R
Rand Aldurra, MClinDent Perio
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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