Actively Recruiting
Effectiveness of Dementia Prevention in Elderly Patients With Mild Cognitive Impairment at Nhân dân Gia Định Hospital, Hồ Chí Minh City
Led by Gia Dinh People Hospital · Updated on 2024-09-19
192
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate the effectiveness of a non-drug intervention program in preventing the progression from mild cognitive impairment to dementia in elderly patients. The study focuses on patients with mild cognitive impairment who still retain memory capacity to learn new skills. It addresses challenges in existing programs, including language barriers and technology use, by developing a culturally appropriate cognitive training program for Vietnamese elderly patients. Participants will receive one of two cognitive training exercise programs lasting 12 weeks. One group will perform home-based exercises supported by physiotherapists or physiatrists as needed, while the other group will attend supervised hospital sessions weekly along with physical training sessions three times a week. Both programs include 19 exercises covering memory, calculation, language, and daily living skills, all based on Vietnamese Ministry of Health guidelines. During the study, participants' progress will be monitored weekly through exercise logs and support opportunities. Researchers will assess effectiveness at 3 and 6 months after starting the program, measuring changes in daily living activities, physical fitness, mental health, adherence, and attendance. The total participation period includes 12 weeks of intervention with ongoing follow-up assessments to track cognitive outcomes and safety.
CONDITIONS
Brief Title
Effectiveness of Non-pharmacological Interventions for Dementia Prevention in Elderly Patients With Mild Cognitive Impairment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with mild cognitive impairment, including cognitive complaints or decline and MMSE score of 24-29
- No major impact of cognitive issues on daily life
- No prior diagnosis of dementia
- Able to travel to the hospital
- Has at least one relative or caregiver to supervise daily activities
- Stable chronic conditions such as diabetes or hypertension
- Provides consent to participate in the study
You will not qualify if you...
- Unable to read or write Vietnamese
- Audio-visual abilities do not meet program requirements
- Have systemic diseases causing secondary cognitive impairment (e.g., brain injury, stroke, brain tumor, parkinsonism, epilepsy, acute heart disease, bone fractures)
- Geriatric Depression Scale score of 5 or higher
- Diagnosed with mental disorders limiting understanding or communication (e.g., schizophrenia, mania, bipolar disorder, anxiety disorders)
- Currently participating in another dementia prevention or medication study within last 3 months
- Taking medications that affect cognition like benzodiazepines, hypnotics, or antipsychotics
- Alcohol abuse or dependence
- Do not agree to participate in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit
Duration - 12 weeks
Participants receive cognitive training exercises and physical training exercises. The home-based group performs exercises at home with weekly assessments, while the supervised group attends weekly supervised cognitive training sessions at the hospital along with physical training sessions three times a week.
Weekly visits for assessments and up to 3 physical training sessions weekly for 12 weeks
Duration - Up to 12 weeks after treatment
Participants are monitored to evaluate the effectiveness of the intervention program, changes in daily living activities, physical fitness, and mental health after completing the training period.
Visits at 3 months and 6 months after randomization
Trial Site Locations
Total: 1 location
1
Nhân dân Gia Định Hospital
Ho Chi Minh City, Vietnam
Actively Recruiting
Research Team
K
Khai Q. Nguyen, M.D
K
Kien G. To, Assoc. Prof
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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