Extremely preterm infants receiving standard care receive very low levels of arachidonic and docosahexaenoic acids.
L De Rooy, H Hamdallah, S C Dyall
https://pubmed.ncbi.nlm.nih.gov/27756480/Actively Recruiting
Led by University of Roehampton · Updated on 2026-05-20
60
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are studying the nutritional content of breast milk from donors, focusing on the levels of important omega-3 and omega-6 fatty acids, docosahexaenoic acid DHA and arachidonic acid. These nutrients are essential for brain development and immune function, but donor milk in the U.K. has been found to have low levels. The study aims to develop and test nutritional information resources to help milk donors improve the quality of their milk, with potential benefits for preterm infants who receive donor milk. This open-label study lasts eight weeks and involves donors from the Countess of Chester Hospital milk bank. Participants complete an initial dietary questionnaire, give blood and breast milk samples, and receive nutritional resources. They are randomly assigned to either receive feedback on their milk DHA levels along with the resources or just the resources. Milk samples are collected at specified weeks and analyzed for fatty acid content. The study also collects detailed diet information through photo diaries submitted via a mobile app. Participants will have baseline and endpoint visits for sample collection, questionnaires, and consultations. Milk and blood samples are analyzed to measure omega-3 fatty acid levels. The study tracks changes in diet and milk DHA content to evaluate the resources effectiveness. Data collection includes dietary photos and feedback on milk DHA for some participants. The study plans to recruit 60 donors over eight months, with ongoing sample storage for future research.
CONDITIONS
Effectiveness of Nutritional Resources for Milk Donors
C
Coralie Falize
J
Jacqueline Chan, PhD
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
University of Roehampton
Lead Sponsor
Countess of Chester NHS Foundation Trust
Collaborating Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 8 weeks
Participants receive nutritional resources and complete diet diaries while providing breast milk and blood samples for analysis. Half of the participants will receive feedback on their breast milk DHA levels.
Initial visit, mid-study sample collection in week 5, and endpoint visit
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Have more questions? Get in touch with our team for quick support
L De Rooy, H Hamdallah, S C Dyall
https://pubmed.ncbi.nlm.nih.gov/27756480/Coralie Falize, M Savage, Yvonne M Jeanes...
https://pubmed.ncbi.nlm.nih.gov/38053371/Isabell Nessel, Laura De Rooy, Minesh Khashu...
https://pubmed.ncbi.nlm.nih.gov/32048312/University of Roehampton
Lead Sponsor
Countess of Chester NHS Foundation Trust
Collaborating Sponsor