Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07395297

Effectiveness of OLE Airway Clearance Therapy in ICU Patients With Pulmonary Infections

Led by Chinese PLA General Hospital · Updated on 2026-02-09

62

Participants Needed

1

Research Sites

118 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to explore the application of Electrical Impedance Tomography (EIT) in evaluating the effectiveness of OLE (Oscillatory Lung Expansion) airway clearance therapy for ICU patients with pulmonary infections. The goal is to understand the treatment response differences in patients with various causes of atelectasis (lung collapse). The study will include adult patients diagnosed with pulmonary infections and admitted to the ICU. The primary endpoint of the study is the peak cough flow (CPF), which measures the patient's ability to clear secretions from the lungs through coughing.

CONDITIONS

Official Title

Effectiveness of OLE Airway Clearance Therapy in ICU Patients With Pulmonary Infections

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clearly diagnosed with pulmonary infection in the ICU, confirmed by microbiological tests or imaging
  • Age 18 years or older
  • Receiving oxygen therapy via nasal cannula or face mask
  • Producing more than 30 ml of sputum per day
  • Patient or legal representative has signed informed consent form
Not Eligible

You will not qualify if you...

  • Pregnant or breastfeeding women
  • Having respiratory or circulatory failure requiring mechanical ventilation or vasopressor support
  • Untreated tension pneumothorax
  • Body Mass Index over 50 kg/m2
  • Rib or severe thoracic deformities
  • Contraindications for EIT use, such as implanted defibrillators, acute chest trauma, or implanted pumps
  • Early withdrawal from the study or incomplete clinical data

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Chinese PLA Hospital

Beijing, Beijing Municipality, China, 10000

Actively Recruiting

Loading map...

Research Team

K

kaifei wang, Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here