Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05045157

Effectiveness of Percutaneous Pulley Release With Infiltration, Versus Infiltration Alone in Trigger Finders

Led by Centre Hospitalier Departemental Vendee · Updated on 2025-09-23

90

Participants Needed

4

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Trigger finger is a mechanical problem characterized by pain and catching of digit in flexion. Histological changes of A1 pulley and synovial proliferation have been identified as factors that prompt trigger finger The first-line treatment of trigger finger is conservative with splinting and corticosteroid injection. If the first infiltration fails, either a second infiltration or surgical sectioning of the pulley is proposed. Surgery can be performed by several techniques (open section, percutaneous section with palpatory guidance, or under ultrasound guidance). Percutaneous A1 pulley release under ultrasound guidance consists of cutting the A1 pulley by a percutaneous insertion with small needle under local anaesthesia. The hypothesis of the study is that percutaneous A1 pulley release under ultrasound guidance followed by a corticosteroid injection would be more effective than a second corticosteroid injection alone on complete resolution of the trigger finger symptoms

CONDITIONS

Official Title

Effectiveness of Percutaneous Pulley Release With Infiltration, Versus Infiltration Alone in Trigger Finders

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient 18 years old or older
  • Trigger finger in thumb or long fingers requiring treatment
  • Quinnell score greater than 1
  • Trigger finger episode confirmed by history or clinical exam
  • Failure of a first corticosteroid injection more than 3 months before joining
  • First corticosteroid injection within 15 months before joining
  • A1 pulley thickening on ultrasound of 0.5 mm or more
  • Ability to understand the study and provide consent
  • Covered by social security
Not Eligible

You will not qualify if you...

  • Multiple symptomatic fingers needing ultrasound-guided pulley release
  • Pregnant, breastfeeding, or potential to become pregnant without contraception
  • Known allergy to corticosteroids or lidocaine
  • On anticoagulant medications
  • Local or general infections or suspected infections
  • Current live vaccines
  • Active viral infections (hepatitis, herpes, varicella, shingles)
  • Severe or uncontrolled high blood pressure
  • Uncontrolled diabetes
  • Progressive cardiovascular disease
  • On hemodialysis
  • Finger prosthesis on the affected finger
  • Tendon fissure seen on ultrasound
  • Inflammatory diseases with tenosynovitis (e.g., rheumatoid arthritis)
  • Previous finger surgery
  • Dupuytren's disease
  • Participating in another interventional drug or device trial
  • Under legal guardianship or protection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Hopital Henri Mondor

Créteil, France, 94000

Actively Recruiting

2

CHD Vendée

La Roche-sur-Yon, France, 85925

Actively Recruiting

3

CHU Nantes

Nantes, France, 44000

Actively Recruiting

4

Hopital Lariboisière

Paris, France, 75010

Actively Recruiting

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Research Team

C

Clémentin GABORIAU

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Effectiveness of Percutaneous Pulley Release With Infiltration, Versus Infiltration Alone in Trigger Finders | DecenTrialz