Actively Recruiting

Phase Not Applicable
Age: 60Years - 90Years
All Genders
Healthy Volunteers
NCT07057973

The Effectiveness of Preoperative Iron Therapy in Improving Anemia After Multi-level Lumbar Fusion in the Elderly

Led by Xuanwu Hospital, Beijing · Updated on 2025-07-10

100

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Preoperative iron therapy has important value in improving the outcomes after lumbar fusion surgery, but there is significant heterogeneity in both domestic and international studies. International studies provide high-level evidence-based evidence for intravenous iron, but lack spinal surgery-specific data; domestic studies focus on the comparison of iron types and the improvement of clinical practice, but high-quality evidence is still insufficient. At present, there are still few studies on preoperative iron therapy in the field of spinal surgery, especially its specific impact on the prognosis of patients after lumbar fusion surgery is still unclear. Therefore, it is particularly important to study the preoperative iron supplementation regimen for lumbar fusion surgery to improve the efficacy and safety. Through multidisciplinary collaboration and technological innovation, preoperative iron therapy is expected to become an important part of accelerated recovery after lumbar fusion surgery.

CONDITIONS

Official Title

The Effectiveness of Preoperative Iron Therapy in Improving Anemia After Multi-level Lumbar Fusion in the Elderly

Who Can Participate

Age: 60Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing multi-segment lumbar spine surgery
  • Iron deficiency anemia patients aged 65 years or older (men: hemoglobin less than 120 g/dL; women: hemoglobin less than 110 g/dL)
  • Completion of relevant questionnaire surveys
Not Eligible

You will not qualify if you...

  • Age less than 65 years
  • Previous spinal surgery for tumors, trauma, or infection
  • Presence of inflammatory or immune diseases, acute kidney injury, progressive cancer, or porphyria cutanea tarda
  • Surgery on non-adjacent spinal segments
  • History of allergy to ferric carboxymaltose or intravenous iron, asthma, atopic dermatitis, or other allergies
  • Decompensated liver cirrhosis or microcytic anemia
  • Incomplete clinical data

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Xuanwu Hospital, Capital Medical University

Beijing, Beijing Municipality, China, 10053

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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