Effectiveness of the Pressure Recording Analytical Method in Predicting Fluid Responsiveness in Pediatric Surgical Critical Care Patients

What this Trial Is About

This research focuses on children aged 0 to 10 years who are undergoing major surgery or have experienced severe trauma with bleeding. It evaluates the Pressure Recording Analytical Method using the Mostcare system, an invasive hemodynamic monitoring device that continuously estimates stroke volume and cardiac output. The study aims to determine if Mostcare can predict which pediatric critical care patients will respond to fluid volume expansion by comparing its measurements with changes detected by trans-thoracic echocardiography. Participants are patients admitted to a pediatric surgical ICU who require volume expansion. The study involves monitoring using the Mostcare device connected to patient monitors, collecting data before and five minutes after fluid infusion. Trans-thoracic cardiac ultrasound is also performed before and three minutes after volume expansion. Patients are grouped by age: less than 6 months, 6 to 12 months, 1 to 6 years, and 6 to 10 years. During the study, children are sedated, intubated, and mechanically ventilated in a supine position. Researchers assess stroke volume variation from Mostcare and compare it to echocardiography changes to identify responders to fluid therapy. Additional cardiac output and stroke volume measurements from Mostcare are also recorded. Participation includes continuous monitoring, data collection, and evaluation of heart function parameters, with observations continuing through fluid infusion and shortly after.

Effectiveness of the Pressure Recording Analytical Method in Predicting Fluid Responsiveness in Pediatric Critical Care Patients