Actively Recruiting

Phase 3
Age: 18Years - 62Years
MALE
NCT06425224

Effectiveness and Safety of TENS Therapy for Premature Ejaculation

Led by Boston Medical Group · Updated on 2024-05-22

129

Participants Needed

1

Research Sites

154 weeks

Total Duration

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AI-Summary

What this Trial Is About

The objective of this clinical trial is to evaluate the effectiveness and safety of transcutaneous posterior tibial nerve stimulation therapy in patients with premature ejaculation. The main question to answer is: Can the effectiveness and safety of transcutaneous electrostimulation of the posterior tibial nerve alone and combined with standard pharmacological treatment be evaluated in men with lifelong premature ejaculation, compared to standard pharmacological treatment with dapoxetine? Patients will: Be randomized in acontrolled clinical trial. Patients with a diagnosis of premature ejaculation who attend Boston Medical Group clinics in Mexico City will be included. Be assigned by randomization to one of three treatment groups: * Group 1: Tens therapy + dapoxetine placebo on demand. * Group 2: Standard treatment (dapoxetine 30 mg as needed) + placebo therapy. * Group 3: Tens therapy + standard treatment (dapoxetine 30 mg as needed).

CONDITIONS

Official Title

Effectiveness and Safety of TENS Therapy for Premature Ejaculation

Who Can Participate

Age: 18Years - 62Years
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Primary premature ejaculation according to International Society for Sexual Medicine definition
  • Age between 18 and 62 years
  • PEDT score greater than 11
  • Stable heterosexual relationship for at least 6 months with interest in continuing during study
  • Sexual activity at least once a week
  • Premature ejaculation lasting at least 6 months
  • Voluntary participation and signing informed consent
Not Eligible

You will not qualify if you...

  • IIEF-EF score less than 26
  • Glaucoma
  • Significant cardiovascular, hepatic, thromboembolic, neurological, locomotor, endocrine, oncological, renal or rheumatological disease
  • History of retroperitoneal surgery, radiotherapy or multiple sclerosis
  • History of mental illness including depression, anxiety, bipolar disorder, or other psychiatric disorders
  • Use of medications affecting ejaculation such as psychiatric drugs, opioid analgesics, alpha blockers
  • Treatment for premature ejaculation in last 3 months
  • Treatment for epileptic syndromes or Parkinson's disease
  • Use of pacemaker or cardiac defibrillator
  • Skin lesions where electrodes would be placed
  • Abuse or dependence on psychoactive substances including alcohol and hallucinogenic drugs
  • Partner who is pregnant or planning pregnancy in next 3 months

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Boston Medical Group

Mexico City, Mexico, 01000

Actively Recruiting

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Research Team

C

Carolina Sandoval, Master

CONTACT

H

Héctor Corredor, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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