Reduced thoracolumbar fascia shear strain in human chronic low back pain.
Helene M Langevin, James R Fox, Cathryn Koptiuch...
https://pubmed.ncbi.nlm.nih.gov/21929806Actively Recruiting
Phase Not Applicable
Age: 18Years - 65Years
All Genders
ID07241559
Comparison of Thoracolumbar Fascia Mobilization and Ultrasound-Guided 5% Dextrose Injection for Chronic Low Back Pain
Led by Ankara City Hospital Bilkent · Updated on 2026-05-07
75
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
Sponsors
A
Ankara City Hospital Bilkent
Lead Sponsor
A
Ankara Training and Research Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research aims to compare the effects of thoracolumbar fascia mobilization and ultrasound-guided 5% dextrose injection on patients with nonspecific chronic low back pain. The study focuses on evaluating changes in pain, lumbar range of motion, and functional disability as primary objectives. Secondary goals include assessing long-term impacts on quality of life, proprioception, and the structural features of the thoracolumbar fascia such as thickness and echogenicity. Participants will be randomly assigned to one of three groups. The first group will receive thoracolumbar fascia mobilization through standardized myofascial release therapy, administered twice weekly for three weeks, totaling six sessions. The second group will receive an ultrasound-guided injection of 10 mL of 5% dextrose into the interfascial plane of the thoracolumbar fascia. The third group will undergo both treatments combined, following the described protocols. Those enrolled will undergo assessments measuring pain by the Visual Analog Scale, lumbar range of motion via digital inclinometer and Modified Schober Test, and functional disability using the Oswestry Disability Index, recorded at baseline and at one and three months post-intervention. Additional evaluations include quality of life surveys, ultrasound imaging of fascia characteristics, and tests of lumbar proprioception. Participation spans from initial screening through follow-ups to monitor safety and outcomes over several months.
CONDITIONS
Brief Title
Effectiveness of Thoracolumbar Fascia Mobilization and Ultrasound-Guided 5% Dextrose Injection in Chronic Low Back Pain
Who Can Participate
Age: 18Years - 65Years
All Genders
Eligibility Criteria
You may qualify if you...
- Male or female patients aged 18 to 65 years
- Low back pain lasting longer than 3 months
- No adequate improvement with medical treatment
- Voluntary participation in the study
You will not qualify if you...
- Age below 18 or above 65 years
- Body mass index (BMI) greater than 30 kg/m8
- Pregnancy or breastfeeding
- Coagulation disorders
- History of spinal surgery
- Inflammatory or malignant diseases
- Local infection at the spine or injection site
- Lumbar disc pathology causing radiculopathy
- Spinal stenosis, spondylolysis, or spondylolisthesis
- Physical therapy or manual therapy within the past 6 months
- Lumbar injections within the past 6 months
- Allergy to injection materials
- Refusal to participate in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - 3 weeks
Participants receive one of the following interventions: thoracolumbar fascia mobilization with six myofascial release sessions twice per week for three weeks, ultrasound-guided thoracolumbar interfascial 5% dextrose injections, or a combination of both treatments.
Twice weekly visits for up to 3 weeks
Follow-up
Duration - 3 months
Participants are evaluated on pain intensity, lumbar range of motion, functional status, quality of life, thoracolumbar fascia characteristics, and lumbar proprioception at one and three months after the treatment.
2 follow-up visits (at 1 month and 3 months post-treatment)
Trial Site Locations
Total: 1 location
1
Ankara Training and Research Hospital
Ankara, Altındağ, Turkey (Türkiye), 06230
Actively Recruiting
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Research Team
B
Barış NACIR, Professor Doctor
B
Büşra ALÇIN, Medical Doctor
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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