Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
NCT07451600

Effectiveness of TMS on Spasticity and Balance for Patients With MS

Led by Ankara Etlik City Hospital · Updated on 2026-04-03

24

Participants Needed

1

Research Sites

39 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Recently, non-invasive brain stimulation modalities such as transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation have become treatment options. Among these methods, rTMS is a non-invasive brain stimulation technique that can affect descending corticospinal pathways, thereby modulating cortical excitability in the motor area where it is applied. This study will examine the effect of rTMS application on spasticity and balance in patients with multiple sclerosis. In addition, the indirect effects of the applications on gait pattern, joint range of motion, and pain will be evaluated.

CONDITIONS

Official Title

Effectiveness of TMS on Spasticity and Balance for Patients With MS

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Being between the ages of 18 and 60
  • Diagnosed with multiple sclerosis for more than six months
  • Spasticity levels between 1 and 3 on the Modified Ashworth Scale in the evaluated extremity
  • Expanded Disability Status Scale (EDSS) score between 0 and 6.5
  • Voluntarily agree to participate in the study
Not Eligible

You will not qualify if you...

  • Poor general health conditions such as heart failure or COPD
  • Presence of wound lesions on the skin
  • Having metal implants in the body
  • Pregnancy
  • Severe infections
  • Diagnosis of malignancy
  • Bleeding disorders
  • Use of a pacemaker
  • Cardiac rhythm disorders
  • Neurological diseases other than multiple sclerosis
  • History of epilepsy
  • History of alcohol use
  • Change in medication within the last 6 months
  • Refusal to participate in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ankara Etlik City Hospital

Ankara, Yenimahalle, Turkey (Türkiye), 06010

Actively Recruiting

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Research Team

M

Melike Çil, specialist

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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