Actively Recruiting
Effects of Adjunct Antimicrobial Photodynamic Therapy in Periodontal Treatment of Patients With Obesity
Led by University of Sao Paulo · Updated on 2026-05-04
24
Participants Needed
1
Research Sites
168 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare the effects of adjuvant antimicrobial photodynamic therapy (aPDT) as an adjuvant of scaling and root planing with scaling and root planing alone for periodontal treatment in patients with periodontal disease and obesity. The main question it aims to answer are: Does adjuvant aPDT improves periodontal health? Are there differences in the proteomic profile of gingival fluid after both treatments? Participants will receive scaling and root planing complemented or not by aPDT. Results will be collected after 1, 3, and 6 months. Researchers will compare adjuvant aPDT treatment to regular treatment to see if it promotes reduction in inflammation and improvement in periodontal health.
CONDITIONS
Official Title
Effects of Adjunct Antimicrobial Photodynamic Therapy in Periodontal Treatment of Patients With Obesity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Obesity (grade II and III classified according to Body Mass Index)
- Stage II to IV periodontitis
- Presence of at least 20 teeth excluding 3rd molars
You will not qualify if you...
- Current smokers
- Consumption of alcohol or drugs
- Kidney disorders
- Pregnancy or lactation
- Use of antibiotics in the last 30 days
- Use of drugs that alter periodontal structures such as phenytoin or ciclosporin
- Periodontal treatment in the last 6 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Bauru School of Dentistry
Bauru, São Paulo, Brazil, 17012-901
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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