Actively Recruiting
Led by Karolinska Institutet · Updated on 2026-01-23
4320
Participants Needed
10
Research Sites
N/A
Total Duration
K
Karolinska Institutet
Lead Sponsor
T
The George Institute
Collaborating Sponsor
Trauma is a major global health concern, and many training programs aim to improve how doctors initially manage trauma patients. Among these, the Advanced Trauma Life Support® (ATLS®) course is the most widely used, having trained over one million physicians worldwide. However, no controlled trials have yet shown whether ATLS® improves patient outcomes, highlighting the need for research to compare ATLS® training with standard care in adult trauma patients. The study compares the effects of ATLS® training with standard care in hospitals in India that treat adult trauma patients. The ATLS® intervention involves a 2.5-day course teaching a standardized approach to trauma care, including primary and secondary surveys, resuscitation, triage, and transfers. Physicians in the experimental group receive this accredited training, while the standard care group consists of usual trauma management by medical and surgical residents without specialized team approaches. Participants are adult trauma patients aged 15 years and older who present to participating emergency departments within 48 hours of injury and are admitted or transferred for admission. Researchers will collect routine hospital data and follow patients for 30 days after emergency department arrival to measure outcomes, focusing primarily on in-hospital mortality. The study uses an opt-out consent process for routine data and obtains informed consent for additional follow-up. Participation may last through hospital stay and 30-day post-arrival monitoring.
CONDITIONS
Effects of Advanced Trauma Life Support® on Adult Trauma Patient Outcomes
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 30 days after arrival at the emergency department
Participants receive trauma care either from physicians trained in Advanced Trauma Life Support or through standard care provided by medical officers and residents.
Care occurs as needed during hospital stay
Total: 10 locations
1
Assam Medical College & Hospital
Dibrugarh, Assam, India, 786003
Actively Recruiting
2
KEM Hospital
Mumbai, Maharashtra, India, 400012
Actively Recruiting
3
Lokmanya Tilak Municipal General Hospital
Mumbai, Maharashtra, India, 400022
Actively Recruiting
4
Hridaysamrat Balasaheb Thackre Mun. Medical college and Dr. R.N. Cooper Hospital
Mumbai, Maharashtra, India, 400056
Actively Recruiting
5
Holy Family Hospital
New Delhi, New Delhi, India, 110025
Actively Recruiting
6
Dayanand Medical College & Hospital
Ludhiana, Punjab, India, 141001
Actively Recruiting
7
Christian Medical College & Hospital
Ludhiana, Punjab, India, 141008
Actively Recruiting
8
Himalayan Institute of Medical Sciences, Swami Rama Himalayan University
Dehradun, Uttarakhand, India, 248016
Actively Recruiting
9
Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital (IPGMER and SSKM Hospital)
Kolkata, West Bengal, India, 700020
Actively Recruiting
10
Government Medical College Hospital
Chandigarh, India, 160030
Actively Recruiting
M
Martin Gerdin Wärnberg, PhD
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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Samriddhi Ranjan, Sara Fälth, Prashant Kharat...
https://pubmed.ncbi.nlm.nih.gov/41630085