Study on Aerobic Exercise Effects on Muscle Tissue in Adults with Colon or Rectal Cancer After Surgery

What this Trial Is About

Researchers are studying the effects of aerobic exercise training compared to attention control on intermuscular adipose tissue in colorectal cancer survivors. The trial focuses on adults aged 18 years or older who have had stage I, II, or III colon or rectal cancer and have completed surgery and other cancer treatments. The study is designed to understand how exercise influences skeletal muscle remodeling in this population. Participants are randomly assigned to one of two groups. One group will engage in aerobic exercise at a dose of 225 minutes per week at moderate to vigorous intensity. The other group will participate in static stretching involving eight major muscle groups, serving as an attention control. The study includes a double-masked design to compare these interventions over the treatment period. Throughout the 12-week study, participants will be closely monitored. Researchers will measure whole-body intermuscular adipose tissue as the primary outcome. Participants will provide written consent and approval from a healthcare professional before enrolling. The study also includes readiness assessments for exercise and tracks adherence and safety during the trial. The total duration and follow-up details are based on the defined study period ending in March 2027.

Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer