Effects of Anesthesia Depth Monitoring on Postoperative Recovery and Cognitive Functions in Older Adults Undergoing Spinal Surgery

What this Trial Is About

Researchers are studying the effects of different anesthesia depth monitoring methods on postoperative recovery and cognitive functions in patients aged 65 and older undergoing surgery for lumbar or cervical disc herniation. The study focuses on reducing risks like intraoperative hypotension, burst suppression, and postoperative delirium in the geriatric population, a group known to experience higher rates of cognitive decline after surgery. This trial evaluates the use of both standard numerical Bispectral Index (BIS) monitoring and the advanced Density Spectral Array (DSA) mode during anesthesia. Participants are randomly assigned to one of three groups: anesthesia depth monitoring guided by hemodynamic parameters to avoid hypotension, monitoring based on numeric BIS index values, or monitoring using the DSA function of the BIS device. All patients receive general anesthesia with continuous monitoring of blood pressure, heart rate, oxygen levels, and brain activity throughout the surgery. Preoperative evaluations collect information on participants' age, weight, health conditions, medications, mental status, and daily activity. During surgery, non-invasive monitors record vital signs and anesthesia depth continuously from induction to emergence. After surgery, cognitive function and mental status are assessed using the Confusion Assessment Method (CAM) scale at multiple time points up to 48 hours postoperatively. Researchers also track medication consumption and monitor anesthesia emergence and brain activity patterns. All data collected are kept confidential and used solely for research. Participation lasts through surgery and the immediate postoperative period.

The Effects of Anesthesia Depth Monitoring on Postoperative Recovery and Cognitive Functions in the Geriatric Patient Population