Actively Recruiting
Effects of an Antioxidant Supplement on Blood Vessel Health
Led by University of Georgia · Updated on 2024-12-09
60
Participants Needed
1
Research Sites
299 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, and the non-Hispanic Black (NHB) population is disproportionately affected. Our research has previously demonstrated that oxidative stress may contribute to reduced vascular function in otherwise healthy NHB adults, potentially predisposing them to the development of hypertension and CVD. This study is designed to examine whether the mitochondria are an important source of oxidative stress-induced vascular dysfunction in healthy NHB adults.
CONDITIONS
Official Title
Effects of an Antioxidant Supplement on Blood Vessel Health
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Self-identify as either non-Hispanic Black or non-Hispanic White
- Men and women aged 18 to 75 years
- Non-hypertensive with systolic blood pressure less than 130 mmHg and diastolic blood pressure less than 85 mmHg
- Low density lipoprotein cholesterol less than 150 mg/dl
- HbA1C less than 6.0%
You will not qualify if you...
- Rash, skin disease, or pigmentation disorders such as psoriasis, eczema, vitiligo, or other inflammatory skin conditions
- Known allergies to latex or adhesives
- Smoking or use of nicotine products within the past year
- Use of illegal or recreational drugs
- Generalized kidney disease
- Taking chloramphenicol, cholestyramine, seizure medications, methotrexate, nitrofurantoin, tetracycline, barbiturates, steroids, phenobarbital/phenytoin, orlistat, or pyrimethamine
- Use of any current medications that may affect cardiovascular control or responses
- Diagnosed or suspected metabolic or cardiovascular disease
- Current pregnancy or breastfeeding
- History of skin or other cancers
- Diagnosed or suspected diabetes with HbA1C 6.0% or higher
- Diagnosis of narcolepsy or any condition affecting body temperature regulation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ramsey Student Center, University of Georgia
Athens, Georgia, United States, 30602
Actively Recruiting
Research Team
S
S. Tony Wolf
CONTACT
M
Melissa Gorejena
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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