Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
Healthy Volunteers
ID06425016

Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy (EARLY): A Randomized Controlled Trial on Early Postoperative Pain

Led by Ricard Corcelles · Updated on 2025-12-10

91

Participants Needed

1

Research Sites

34 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying the effects of two types of bariatric surgery, laparoscopic sleeve gastrectomy (LSG) and robotic sleeve gastrectomy (RSG), in adults eligible for sleeve gastrectomy under NIH guidelines. This interventional trial aims to compare early postoperative pain between the two surgical approaches, as well as surgeon comfort and patient quality of life. Additional outcomes include 30-day perioperative results, complications, serious adverse events, resolution of obesity-related conditions, and weight loss one year after surgery. The study randomly assigns participants to receive either standard laparoscopic sleeve gastrectomy or robotic-assisted sleeve gastrectomy. Both procedures involve removing part of the stomach to promote weight loss, but robotic surgery offers potential benefits such as better 3D visualization and improved surgeon ergonomics. All surgeries occur at a single center, and each participant undergoes only one type of surgery during the trial. Participants will be monitored closely after surgery to assess pain levels using morphine dose consumption and pain scores at 1, 7, and 30 days post-operation. Quality of life will also be evaluated at 30 days, and surgeon ergonomics will be assessed during surgery. Researchers will track complications and medical improvements up to one year, including weight loss expressed as percent of excess weight lost. The trial will last until April 2027, with various follow-up assessments scheduled throughout the year.

CONDITIONS

Brief Title

Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy

Who Can Participate

Age: 18Years - 70Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Eligible for sleeve gastrectomy based on current NIH guidelines
  • Able to give consent
  • Medically cleared to undergo elective surgery
  • Able to tolerate general anesthesia
  • Aged between 18 and 70 years
Not Eligible

You will not qualify if you...

  • Previous bariatric surgery
  • Emergency surgery cases
  • Chronic opioid use (daily use for at least 3 months)
  • Unable to sign written consent form

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - Up to 1 week

Participants undergo either robotic-assisted or laparoscopic sleeve gastrectomy followed by early post-operative care focusing on pain management.

1 surgical visit and daily assessments during hospital stay

Post-operative Follow-up

Duration - 30 days (±15 days)

Participants are followed to assess pain, quality of life, and recovery at multiple time points after surgery.

3 follow-up visits on approximately postoperative days 1, 7, and 30

Trial Site Locations

Total: 1 location

1

Cleveland Clinic

Cleveland, Ohio, United States, 44195

Actively Recruiting

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Research Team

R

Ricard Corcelles Codina, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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