Actively Recruiting
Effects of Barley Green on Visceral Fat Area in the Human Body and Investigation Into the Associated Mechanism of Intestinal Microbiota
Led by Peking University People's Hospital · Updated on 2026-03-30
66
Participants Needed
1
Research Sites
88 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study was to investigate the changes in visceral fat area and associated indicators in individuals with high body fat percentage under the intervention of barley green, elucidate the clinical efficacy of barley green on human visceral fat, and preliminarily explore the mechanism by which barley green influences human visceral fat through gut microbiota analysis. Participants with high body fat percentage were recruited from the Clinical Nutrition Department of Peking University People's Hospital and randomly assigned to either an intervention group or a control group. The intervention group received a regimen combining barley green supplementation with a calorie-restricted balanced diet plan, while the control group followed only the calorie-restricted balanced diet plan. General clinical data were collected, nutritional assessments were conducted, and dynamic analyses of body composition and metabolism were performed. Venous blood samples were obtained for the measurement of metabolic and inflammation-related indices as well as gut microbiota characterization. By observing and comparing differences in visceral fat area and related parameters, as well as gut microbiota profiles between the two groups, this study provides a scientific foundation for the clinical application of barley green in medical nutrition interventions targeting populations with high body fat percentage.
CONDITIONS
Official Title
Effects of Barley Green on Visceral Fat Area in the Human Body and Investigation Into the Associated Mechanism of Intestinal Microbiota
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 65 years, any gender
- Body fat percentage above 20% for males or above 28% for females
- Visceral fat area greater than 100 cm2
- Willing to undergo assessments and provide informed consent
You will not qualify if you...
- Currently using weight-loss medications, insulin resistance drugs, or anti-inflammatory agents affecting inflammation
- Taking nutritional supplements or functional foods known to reduce body fat or visceral fat
- Regularly consuming prebiotics, probiotics, or microbiota-modulating agents
- Having diseases seriously affecting nutrient digestion or absorption such as chronic diarrhea or active gastrointestinal conditions
- Having cardiovascular or cerebrovascular diseases, grade 3 hypertension, stroke, chronic hepatitis, cancers, anemia, psychiatric or cognitive disorders, epilepsy, acute gout, kidney stones, or kidney failure
- Having liver dysfunction with ALT or AST levels over three times the normal limit or kidney dysfunction with high serum creatinine
- Having active infections like tuberculosis or HIV/AIDS
- Severe allergies to any study product components
- Pregnant or breastfeeding
- Physical disabilities or other significant health conditions that make participation unsuitable as judged by investigators
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Peking University People's Hospital
Beijing, Xicheng District, China, 100044
Actively Recruiting
Research Team
M
Mingxuan Cui
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here