Actively Recruiting
Effects of Blocking Blue Light at Night Post CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH
Led by West Virginia University · Updated on 2026-04-20
80
Participants Needed
1
Research Sites
292 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Purpose The purpose of this study is to determine whether filtering out blue light at nighttime reduces post-surgical inflammation and/or moderates cognitive decline and mood and sleep alterations in patients undergoing elective CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH surgery. If manipulating nighttime light in hospital rooms improves patient outcomes, then it would be a relatively easy and inexpensive innovation that could reduce post-surgical complications and save millions of dollars per year in health care costs by shortening the length of hospital stays and reducing morbidity. The investigators aim to determine the relationship between inflammation and cognitive dysfunction after cardiac surgery.
CONDITIONS
Official Title
Effects of Blocking Blue Light at Night Post CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women undergoing elective (non-emergency) on-pump CABG surgery, AVR, MVR, CABG AVR, CABG MVR, or SAH
- No history of diagnosed psychiatric disorders or organ failure
You will not qualify if you...
- Diagnosis or evidence of dementia or other cognitive deficits
- Diagnosed psychiatric disorder including depression and anxiety
- Organ failure such as kidney (creatine > 1.5 mg/dL), liver, or others
- Chronic obstructive pulmonary disease
- Any immune disorder
- Acute infection
- Prior cardiac surgery
- Elective aneurysms
- Combined cardiac operations
- Left main stenosis greater than 70%
- Left ventricular ejection fraction lower than 0.5
- Any condition increasing likelihood of blood transfusion during or after surgery
- Clotting disorder
- Suspected reading comprehension below 8th grade level in English
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
West Virginia University Heart and Vascular Institute
Morgantown, West Virginia, United States, 26506
Actively Recruiting
Research Team
J
James C Walton, PhD
CONTACT
P
Pallavi Sharma, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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