Actively Recruiting

Phase Not Applicable
Age: 18Years - 40Years
MALE
Healthy Volunteers
ID06949995

Effects of Blood Flow Restriction on Post-Exercise Recovery in Amateur Runners: A Stratified Randomized Controlled Trial

Led by Paulista University · Updated on 2026-05-14

34

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of combining active recovery (AR) and blood flow restriction (BFR) on post-exercise recovery in healthy amateur male runners aged 18 to 40 years who run faster than 5:30 min/km. The study aims to determine if using both techniques together offers better recovery outcomes compared to active recovery alone or complete rest after exercise. Participants will be randomly assigned to one of three groups: active recovery with blood flow restriction using a pneumatic cuff at 60% occlusion pressure for 10 minutes, active recovery without restriction for 10 minutes, or passive rest without movement for 10 minutes. All participants will complete baseline assessments and a muscle stress protocol before applying their assigned recovery method. During the study, researchers will assess heart rate variability, muscle soreness, recovery perception, discomfort, effort, cellular integrity, pain threshold, muscle tone, stiffness, elasticity, muscle power, plantar flexor strength, and aerobic capacity at baseline and at intervals up to 96 hours after exercise. Participants will provide informed consent and may allow data sharing with universities or regulatory authorities. The study includes follow-up evaluations immediately and at 24, 48, 72, and 96 hours post-exercise.

CONDITIONS

Brief Title

Effects of Blood Flow Restriction on Post-Exercise Recovery in Amateur Runners

Who Can Participate

Age: 18Years - 40Years
MALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male individuals aged 18 to 40 years
  • Healthy amateur runners running faster than 5:30 min/km
  • Able and willing to perform exercise and recovery protocols
  • Agree to sign informed consent form
  • No use of ergogenic supplements to improve performance or vasoactive medications
  • No history of knee surgery or recent lower limb musculoskeletal injury in the last six months
  • No presence of diabetes, high blood pressure, inflammatory, psychiatric, cardiovascular, respiratory, or rheumatological diseases
  • Not dependent on alcohol, drugs, or tobacco use
Not Eligible

You will not qualify if you...

  • Presence of any health problems preventing continuation in the study
  • Wish to leave the study at any time
  • Refusal to sign the informed consent form

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Baseline Assessment

Duration - 1 day

Participants undergo baseline assessments before the exercise and recovery protocols.

1 visit (in-person)

Muscle Stress and Recovery Intervention

Duration - 10 minutes

Participants perform a muscle stress protocol followed by one of three recovery strategies: active recovery with blood flow restriction, active recovery alone, or passive rest.

1 visit (in-person)

Post-Exercise Follow-up

Duration - 4 days

Participants complete follow-up evaluations immediately, and at 24, 48, 72, and 96 hours after exercise to assess recovery outcomes.

5 visits (in-person)

Trial Site Locations

Total: 1 location

1

Franciele Marques Vanderlei

Presidente Prudente, São Paulo, Brazil, 19060-900

Actively Recruiting

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Research Team

F

Franciele Marques Vanderlei, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

3

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