Actively Recruiting

Phase 1
Age: 18Years - 30Years
All Genders
Healthy Volunteers
NCT06686914

The Effects of Cannabidiol on the Driving Performance of Healthy Adults by Dose and Sex

Led by West Virginia University · Updated on 2025-10-31

300

Participants Needed

1

Research Sites

200 weeks

Total Duration

On this page

Sponsors

W

West Virginia University

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The objectives/purpose of this study are to comprehensively investigate the effects of non-prescription CBD on driving performance, drowsiness, sedation, and cognitive function in a large sample of healthy adults aged 18-30 years, with additional characterization of effects by dose and by sex, using a rigorous RCT design which will naturally mitigate confounding factors.

CONDITIONS

Official Title

The Effects of Cannabidiol on the Driving Performance of Healthy Adults by Dose and Sex

Who Can Participate

Age: 18Years - 30Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Possess a current drivers' license
  • Driven a motor vehicle at least once in the past 30 days
  • Able to read English
  • Test negative for all substances on a urine drug test and complete a test drive to ensure the absence of simulation sickness
  • Not taking any daily prescription medications (excluding birth control)
  • Not diagnosed with any serious chronic disease by a licensed healthcare provider (including but not limited to Alzheimer's and related dementias, Parkinson's disease or other neurodegenerative disorder, major depressive or anxiety disorder, schizophrenia or other serious mental illness, arrhythmias, cataracts, glaucoma, chronic obstructive pulmonary disease, diabetes, epilepsy, sleep apnea, and fibromyalgia)
  • Have an individual willing to drive them home after testing or be taken home by study staff after testing
Not Eligible

You will not qualify if you...

  • Currently smoke, vape or use tobacco products, used CBD in the past 30 days
  • Used illegal drugs in the past 30 days (e.g., cocaine/crack, heroin, methamphetamine, 3,4-methylenedioxy-methamphetamine, inhalants, phencyclidine, lysergic acid diethylamide, psilocybin mushrooms, or marijuana)
  • Are pregnant or lactating at time of study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

West Virginia University

Morgantown, West Virginia, United States, 26506

Actively Recruiting

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Research Team

T

Toni M Rudisill, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

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